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Fundamentals of MALDI-ToF-MS analysis : applications in bio-diagnosis, tissue engineering and drug delivery /
This book presents the fundamentals and applications of Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF-MS) technique. It highlights the basic principles, the history of invention as well as the mechanism of ionization and mass determination using this techniq...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Singapore :
Springer,
[2016]
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| Colección: | SpringerBriefs in applied sciences and technology. Forensic and medical bioinformatics.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 082 | 0 | 4 | |a 543/.65 |2 23 |
| 049 | |a UAMI | ||
| 100 | 1 | |a Hosseini, Samira, |e author. | |
| 245 | 1 | 0 | |a Fundamentals of MALDI-ToF-MS analysis : |b applications in bio-diagnosis, tissue engineering and drug delivery / |c Samira Hosseini, Sergio O. Martinez-Chapa. |
| 264 | 1 | |a Singapore : |b Springer, |c [2016] | |
| 264 | 4 | |c ©2017 | |
| 300 | |a 1 online resource (xi, 68 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a SpringerBriefs in applied sciences and technology, Forensic and medical bioinformatics, |x 2191-530X | |
| 504 | |a Includes bibliographical references. | ||
| 588 | 0 | |a Online resource; title from PDF title page (SpringerLink, viewed August 26, 2016). | |
| 505 | 0 | |a Preface; Acknowledgment; Contents; 1 Principles and Mechanism of MALDI-ToF-MS Analysis; Abstract; 1.1 Background of MALDI-ToF-MS; 1.2 Applications of MALDI-ToF-MS; 1.2.1 Biochemistry; 1.2.2 Organic Chemistry; 1.2.3 Polymer Chemistry; 1.2.4 Microbiology; 1.2.5 Medicine; 1.2.6 Nanotechnology; 1.3 Ionization Mechanism; 1.4 Time of Flight Mass Spectrometry Mechanism; 1.5 Detection Modes; 1.5.1 Linear Mode; 1.5.2 Reflection Mode; 1.6 Laser Range in MALDI; 1.7 Matrix Selection; 1.7.1 Limitations of Matrices; 1.8 Ionizing Agent Selection; 1.9 Fundamentals of Sample Preparation for MALDI Analysis. | |
| 505 | 8 | |a 1.9.1 Analyzable and Non-analyzable Polymers1.9.2 Sample Preparation Techniques; 1.9.2.1 Dried-Droplet; 1.9.2.2 Fast Crystallization; 1.9.2.3 Spin Coating; 1.9.2.4 Layer by Layer; 1.9.2.5 Electrospray Deposition; 1.10 Mass Discrimination; 1.10.1 Alternative Solutions for Overcoming Mass Discrimination; 1.11 MALDI Coupling; 1.11.1 Ion-Mobility Time of Flight Mass Spectrometry (IMS-ToF-MS); 1.11.2 Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR-MS); 1.11.3 Thin Layer Chromatography (TLC); 1.11.4 Size Exclusion Chromatograph (SEC); References. | |
| 505 | 8 | |a 2 Fundamentals of Biosensors and Application of MALDI-ToF-MS in Bio-diagnostic DomainAbstract; 2.1 Biosensors; 2.2 Synthesis of Poly Methyl Methacrylate-Co-Methacrylic Acid P(MMA-Co-MAA) and Preparation of the Biochips; 2.3 Sample Preparation for MALDI Analysis; 2.4 MALDI Data Interpretation; 2.4.1 Different Species as the Possible Products of Soft Ionization; 2.4.2 General Structure of P(MMA-Co-MAA); 2.4.3 MALDI Analysis of PMMA; 2.4.4 MALDI Analysis of P(MMA-Co-MAA); 2.4.5 End-Group Analysis; 2.5 Role of MALDI Analysis in Bio-sensing Application of P(MMA-Co-MAA); 2.5.1 Reaction's Parameters. | |
| 505 | 8 | |a 2.5.2 Chemistry Aspect2.5.3 Physical Aspect; References; 3 Fundamentals of Tissue Engineering and Application of MALDI-ToF-MS in Analysis of the Scaffold Materials; Abstract; 3.1 Tissue Engineering; 3.2 Synthesis of Poly Octanediol Citrate Acid-Sebacate Acid P(OCS) and Preparation of the Scaffold; 3.3 MALDI Analysis of P(OCS) and Sample Preparation; 3.4 MALDI Data Interpretation; 3.5 Role of MALDI Analysis in Tissue Engineering Application of P(OCS); 3.5.1 Reaction's Parameters; 3.5.2 Chemistry Aspect; 3.5.3 Mechanical Aspect; References. | |
| 505 | 8 | |a 4 Fundamentals of Drug Delivery Systems and Application of MALDI-ToF-MS in Drug DeliveryAbstract; 4.1 Drug Delivery; 4.2 Synthesis of PCLT-CA and Preparation of Elastomeric Films and Coatings; 4.3 Sample Preparation for MALDI Analysis; 4.4 MALDI Data Interpretation; 4.5 The Role of MALDI Analysis in Drug Delivery Application of PCLT-CA; 4.5.1 Chemistry Aspect; 4.5.2 Mechanical Aspect; References; Summary. | |
| 520 | |a This book presents the fundamentals and applications of Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF-MS) technique. It highlights the basic principles, the history of invention as well as the mechanism of ionization and mass determination using this technique. It describes the fundamental principles and methods for MALDI spectra interpretation and determination of exact chemical structures from experimental data. This book guides the reader through the interpretation of MALDI data where complex macromolecular spectra are simplified in order to present the major principles behind data interpretation. In addition, each chapter describes how MALDI-ToF-MS analysis provides necessary understanding of the copolymer systems that have been designed for specialized biomedical applications. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Matrix-assisted laser desorption-ionization. | |
| 650 | 2 | |a Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | |
| 650 | 6 | |a Désorption-ionisation laser assistée par matrice. | |
| 650 | 7 | |a SCIENCE |x Chemistry |x Analytic. |2 bisacsh | |
| 650 | 7 | |a Matrix-assisted laser desorption-ionization |2 fast | |
| 700 | 1 | |a Martínez Chapa, Sergio Omar, |e author. | |
| 758 | |i has work: |a Fundamentals of MALDI-ToF analysis (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFVbBvGY88MHMVH6hCTGVy |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Hosseini, Samira. |t Fundamentals of MALDI-ToF-MS analysis. |d Singapore : Springer, [2016] |z 9789811023552 |z 9811023557 |w (OCoLC)953709754 |
| 830 | 0 | |a SpringerBriefs in applied sciences and technology. |p Forensic and medical bioinformatics. | |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=4648924 |z Texto completo |
| 938 | |a EBL - Ebook Library |b EBLB |n EBL4648924 | ||
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| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n cis35599436 | ||
| 938 | |a YBP Library Services |b YANK |n 13132800 | ||
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