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Post-genomic approaches in drug and vaccine development /
Over the past decade genome sequencing projects and the associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Aalborg, Denmark :
River Publishers,
2015.
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| Colección: | River Publishers series in research and business chronicles: biotechnology and medicine ;
v. 5. |
| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | Over the past decade genome sequencing projects and the associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, understand their role in physiological pathways and associated diseases, with the aim to translate these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic and metabolomic approaches. This book focuses on some key advances in the field. Technical topics discussed in the book include: * Drug discovery * Target identification and prioritization * Hypothesis driven multi-target drug design * Genomics in vaccine development * Gene regulatory networks * Vaccine design and development * Prediction of drug side effects in silico. |
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| Descripción Física: | 1 online resource (451 pages) |
| Bibliografía: | Includes bibliographical references at the end of each chapters and index. |
| ISBN: | 9788793102859 8793102852 9781003339090 1003339093 9781000795714 1000795713 9781000792393 1000792390 |