Cargando…

Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry.

Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications. Advances in polymer science and the intr...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Thakur, Vijay Kumar
Otros Autores: Thakur, Manju Kumari
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken : Wiley, 2015.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Half Title page; Title page; Copyright page; Dedication; Preface; About the Editors; Chapter 1: Gellan as Novel Pharmaceutical Excipient; 1.1 Introduction; 1.2 Structural Properties of Gellan; 1.3 Physiochemical Properties of Gellan; 1.4 Pharmaceutical Applications of Gellan; 1.5 Conclusion and Future Perspectives; References; Chapter 2: Application of Polymer Combinations in Extended Release Hydrophilic Matrices; 2.1 Extended Release Matrices; 2.2 Polymer Combinations Used in ER matrices; 2.3 Combination of Non-Ionic with Ionic Polymers; 2.4 Combinations of Ionic Polymers.
  • 2.5 Other Polymer Combinations2.6 Effect of Dissolution Method (Media) on Drug Release from ER Matrices Containing Polymer Combinations; 2.7 Main Mechanisms of Drug-Polymer and/or Polymer-Polymer Interaction in ER Formulations; 2.8 Summary and Conclusions; References; Chapter 3: Reagents for the Covalent Attachment of mPEG to Peptides and Proteins; 3.1 Introduction; 3.2 General Considerations about PEG Reagents and PEGylation Reactions; 3.3 PEGylation of Amino Groups; 3.4 PEGylation of Thiol Groups; 3.5 Reversible PEGylation; 3.6 Enzymatic PEGylation; 3.7 PEGylation of Carbohydrates Residues.
  • 3.8 PEGylation by Click Chemistry3.9 Other PEGylations; 3.10 Actual Trends; 3.11 Conclusions; Acknowledgements; References; Chapter 4: Critical Points and Phase Transitions in Polymeric Matrices for Controlled Drug Release; 4.1 Introduction; 4.2 Matrix Systems; 4.3 Polymers Employed in the Manufacture of Matrix Systems; 4.4 Polymer Properties Affecting Drug Release from Matrix Systems; 4.5 Percolation Theory; 4.6 Critical Points in Matrix Systems; 4.7 Case-Study: Characterization of a New Biodegradable Polyurethane PU (TEG-HMDI) as Matrix-Forming Excipient for Controlled Drug Delivery.
  • 4.8 Conclusions and Future PerspectivesReferences; Chapter 5: Polymeric Systems in Quick Dissolving Novel Films; 5.1 Introduction; 5.2 Preparation Methods of Novel Quick Dissolving Films; 5.3 Polymers and Blends for Utilization in Different Quick Dissolving Films; 5.4 Polymers in Novel Quick Dissolving Films; 5.5 Role of Plasticizers in Novel Quick Dissolving Film; 5.6 Characterization Procedure Listed in the Literature for Fast Dissolving Films; 5.7 Conclusion and Future Perspectives; References.
  • Chapter 6: Biomaterial Design for Human ESCs and iPSCs on Feeder-Free Culture toward Pharmaceutical Usage of Stem Cells6.1 Introduction; 6.2 Analysis of the Pluripotency of hPSCs; 6.3 Physical Cues of Biomaterials that Guide Maintenance of PSC Pluripotency; 6.4 Two-Dimensional (2D) Culture of hPSCs on Biomaterials; 6.5 Three-Dimensional (3D) Culture of hPSCs on Biomaterials; 6.6 hPSC Culture on PDL-Coated Dishes with the Addition of Specific Small Molecules; 6.7 Conclusion and Future Perspective; Acknowledgements; References; Chapter 7: New Perspectives on Herbal Nanomedicine.