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Advanced LC-MS Applications in Bioanalysis /

LC-MS is a key tool in bioanalysis of drugs and their metabolites. This book covers the most exciting, novel and challenging applications of LC-MS with a focus on problem solving and particularly complex or advanced analyses. Coverage ranges from sample preparation through chromatographic separation...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Yuan, Long
Otros Autores: Bergeron, Annik, Mess, Jean-Nicholas, Zhong, Dafang, Ji, Qin C.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Shanghai Institute of Materia Medica, China, Bristol-Myers Squibb Co., USA & Algorithme Pharma Inc., Canada : Future Science Ltd, 2015, ©2015.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Advanced LC-MS applications in bioanalysis / Long Yuan, Annik Bergeron, Jean-Nicholas Mess, Dafang Zhong & Qin C. Ji
  • Method development strategies in bioanalysis / Shefali R. Patel & Naidong Weng
  • High-throughput methods for LC-MS bioanalysis / Xianmei Cai & Wilson Shou
  • Phospholipids-based matrix effect elimination techniques / Vincenzo Pucci
  • Advanced sample preparation techniques prior to LC-MS / Yong Q. Tang
  • Complex sample types / Bernd A. Bruenner, Mary C. Wells & Christopher A. James
  • Advanced separation methods / Roger N. Hayes
  • Multidimensional separation methods / Graeme T. Clark
  • Computational approaches in developing accelerated chiral liquid chromatography techniques for mass spectral assays Min Meng, Laixin Wang & Scott Reuschel
  • Novel MS detection methods / Pan Deng & Dafang Zhong
  • Novel calibration approaches for LC-MS bioanalysis / Aimin Tan, Kayode Awaiye & Fethi Trabelsi
  • Liquid chromatography mass spectrometry quantitative bioanalysis of proteins / Long Yuan, Annik Bergeron, Jean-Nicholas Mess, Fabio Garofolo, Anne-Françoise Aubry & Qin C. Ji
  • Dried blood spots and their role in bioanalysis / John S. Williams & Christopher L. Brummel
  • Analytical approaches to support microdose studies in drug discovery and development / Jim X. Shen, Yue Zhao & Xiaohui (Sophia) Xu.