Cargando…
Drug-device combinations for chronic diseases /
This book covers two areas, the first detailing the concepts and technologies of drug-device combination products. The second area includes case studies of important products that either significantly shape our technologies and thinking, or contribute to current healthcare practice. The book: -Discu...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
John Wiley & Sons,
2015.
|
| Edición: | 1st |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Wiley
- Society for Biomaterials Series; Title Page; Copyright; Foreword; Preface; Part I: Backgrounds; Chapter 1: Addressing Medical Device Challenges With Drug-Device Combinations; 1.1 Introduction; 1.2 The Host Foreign Body Reaction; 1.3 Device-Based Thrombosis; 1.4 Biomaterials-Associated Infection; 1.5 Combination Medical Devices; 1.6 Future Directions; Acknowledgment; References; Chapter 2: Historical Survey of Drug Delivery Devices; 2.1 Introduction; 2.2 The Origins of Drug Delivery Devices; 2.3 Classification of Drug Delivery Devices.
- 2.4 An Early Example of Designed Drug Delivery Systems: Osmotic Drug Delivery Systems2.5 Another Early Delivery System Based on Membrane-Controlled Release: Ocular Delivery Systems; 2.6 EARLY SUCCESSES IN THE USE OF MEMBRANE AND HYBRID SYSTEMS: TRANSDERMAL PATCHES; 2.7 Early Efforts to Target Drug Delivery: Mucoadhesive Drug Delivery Systems; 2.8 Drug Delivery in Combination Products: Drug-Eluting Stents; 2.9 The Advent of Microfabricated Drug Delivery Devices; 2.10 Conclusions and Directions; References; Chapter 3: Development of Combination Product Drug Delivery Systems; 3.1 Introduction.
- 3.2 Oral Delivery3.3 Dermal Delivery; 3.4 Implantable Delivery; 3.5 Conclusions; Acknowledgments; References; Chapter 4: Drug-Material Interactions, Materials Selection, and Manufacturing Methods; 4.1 Introduction; 4.2 Drug-Device Interactions and Tests; 4.3 Material Selection and Development; 4.4 Manufacturing Methods for Combining Drugs into Devices; 4.5 Summary; References; Part II: Products; Chapter 5: Steroid-Releasing Lead; 5.1 Introduction; 5.2 Background; 5.3 The Quest for Low-Threshold Leads; 5.4 The Evolution of Steroid-Eluting Electrodes.
- 5.5 Inflammation Mechanisms and the Effects of Steroid Elution5.6 The Mechanism of Chronic Steroid Elution: Does the Steroid Run Out?; 5.7 Other Possible Drug Elution Systems; 5.8 Summary; References; Chapter 6: Thromboresistant Vascular Graft; 6.1 Introduction; 6.2 Vascular Grafting for Peripheral Arterial Reconstruction; 6.3 ePTFE Vascular Grafts; 6.4 Early Heparin Surfaces; 6.5 Carmeda Bioactive Surface Technology; 6.6 Understanding CBAS Surface Hemocompatibility; 6.7 Early Clinical Experience With CBAS Surface; 6.8 Product Development.
- 6.9 Clinical Performance, Clinical Usefulness, and Clinical Challenges6.10 Heparin-Induced Thrombocytopenia; 6.11 Working Hypothesis; 6.12 Summary; References; Chapter 7: Device-Enabled Drug Infusion Therapies; 7.1 Introduction; 7.2 Basic Device Requirements and Routes of Infusion; 7.3 Infusion Therapy Components and Functions; 7.4 Clinical Applications; 7.5 Advantages; 7.6 Interactions; 7.7 Challenges; 7.8 Development and Regulatory Approval of New Infusion Therapies; 7.9 New Indications in Development; 7.10 Future Possibilities for Infusion Technology; References.