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Metabolic acidosis : a guide to clinical assessment and management /
This timely volume provides an overview to the causes, effects on systems and clinical approaches of metabolic acidosis. Beginning with a basic understanding of the physiology, pathophysiology and development of this disease, subsequent chapters cover the characteristics and context of the processes...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer,
2016.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Preface; Contents; Contributors; Chapter 1: Overview of Acid-Base Physiology; Introduction; Maintenance of Normal Acid-Base Homeostasis; Systemic and Renal Acid-Base Homeostasis; Organ Contributors to Systemic Acid-Base Status; References; Chapter 2: Metabolic Acidosis: Physiology, Presentation, and Diagnosis; Introduction; The Use of the Serum Anion Gap [1, 2]; Hyperchloremic Metabolic Acidosis [1, 2, 4, 5]; Metabolic Acidosis with Increased Anion Gap [1, 2, 4, 8]; Overproduction Acidosis; Anion Gap Acidosis Due to Acid Ingestion or Retention; References.
- Chapter 3: Etiologic Causes of Metabolic Acidosis I: The High Anion Gap AcidosesHigh Anion Gap Acidoses; Lactic Acidosis; Pathophysiology; Pathogenesis and Clinical Spectrum; Translational Approach; d-Lactic Acidosis; Ketoacidosis; Diabetic Ketoacidosis; Alcoholic Ketoacidosis; Drug- and Toxin-Induced Acidosis; Salicylate; The Osmolar Gap and Toxin-Induced Metabolic Acidosis; Ethylene Glycol; Methanol; Pyroglutamic Acid; Propylene Glycol; Uremia; Pathophysiological Basis of Correction of Acidosis of Chronic Kidney Failure; References.
- Chapter 4: Etiologic Causes of Metabolic Acidosis II: Normal Anion Gap AcidosesNon-Anion Gap (Hyperchloremic) Metabolic Acidoses; Disorders of Impaired Kidney Bicarbonate Reclamation: Proximal Renal Tubular Acidosis; Pathophysiology; Disorders of Impaired Net Acid Excretion with Hypokalemia: Classical Distal Renal Tubule Acidosis; Pathophysiology; Disorders of Impaired Net Acid Excretion with Hyperkalemia: Generalized Distal Nephron Dysfunction (Type 4 Renal Tubular Acidosis); Drug-Induced Kidney Tub ular Secretory Defects; Impaired Renin-Aldosterone Elaboration.
- Voltage Defect of Collecting Duct Disorders of Impaired Net Acid Excretion and Impaired Bicarbonate Reclamation with Normokalemia: Acidosis of Progressive Kidney Failure; References; Chapter 5: The Use of Bedside Urinary Parameters in the Evaluation of Metabolic Acidosis; Introduction; Urine pH; Limitations and Caveats in the Interpretation of Urine pH; Urine Bicarbonate; Urine Electrolytes and the Urine Anion Gap; Provocative Tests of Distal Acidification; Ammonium Chloride Test; Sodium-Dependent Tests of Distal H+ Secretion; Sodium Sulfate; Furosemide Test; Amiloride Test.
- Urinary PCO2 as an Index of Collecting Tubule H SecretionReferences; Chapter 6: Pathophysiologic Approach to Metabolic Acidosis; Introduction; Plasma Chloride and the Plasma Anion Gap; Acid Excretion by the Kidney in Metabolic Acidosis; Titratable Acids; Ammonium (NH4+); Citrate; Net Acid Excretion; Implications for Alkali Therapy; References; Chapter 7: Dietary Contributions to Metabolic Acidosis; Case Vignette; Question; Determinants of Blood pH (Review); Metabolism of Dietary Substrates; Effects of Dietary Substrates on Systemic Acid-Base Balance; The "Trade-Off" Hypothesis.