Human Drug Targets : a Compendium for Pharmaceutical Discovery /
Clasificación: | Libro Electrónico |
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Autor principal: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Wiley-Blackwell,
2015.
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Edición: | 1st |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Title Page; Table of Contents; Preface; Reference; Chapter 1: Introduction; 1.1 Magic bullets; 1.2 Background to modern pharmacology; 1.3 Drug and therapeutic targets in the biomedical literature; 1.4 How many drug targets are there?; 1.5 Screening for active molecules; References; Chapter 2: Overview of the drug target compendium; 2.1 Introductory comments; 2.2 Selection of entries; 2.3 Organization of entries; 2.4 Summary of data entries; 2.5 How to use this book; 2.6 Final comments; References; Chapter 3: Cell surface and secreted proteins; 3.1 G-protein-coupled receptors (GPCRs).
- 3.2 Nuclear hormone receptors (NHRS)3.3 Cytokines and receptors; 3.4 Adhesion molecules; 3.5 Host defence molecules; 3.6 Transporters and channels; References; Chapter 4: Enzymes: Part 1; 4.1 Signalling enzymes; 4.2 Protein modification; References; Chapter 5: Enzymes: Part 2; 5.1 Lipids and related; 5.2 Amino acids and related; 5.3 Nucleotides and related; 5.4 Carbohydrates and related; 5.5 Vitamins, cofactors and related; 5.6 DNA-processing enzymes; 5.7 RNA-processing enzymes; 5.8 Stress response and homeostasis; 5.9 Miscellaneous enzymes; References.
- Chapter 6: Remaining annotated entries grouped by subcellular location6.1 Cell surface and secreted proteins; 6.2 Cytoskeleton; 6.3 Cytoplasm to nucleus; 6.4 Nucleus; 6.5 Internal membranes and organelles; 6.6 Cytoplasmic proteins; 6.7 Subcellular location not annotated; Chapter 7: Non-coding RNAs; References; End User License Agreement.