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Translational medicine : global concepts, tools and technology /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Academic Press,
2015.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; TRANSLATIONAL MEDICINE: TOOLS AND TECHNIQUES; Copyright; Contents; List of Contributors; About the Editor; Preface; Acknowledgments; 1
- New Developments in the Use of Biomarkers in Translational Medicine; INTRODUCTION; BIOMARKERS AS PART OF A TRANSLATIONAL STRATEGY; NEW TYPES OF BIOMARKERS; From Blood- to Tissue-Specific Biomarkers; From Static to Functional Biomarker Assays; From Static Ex Vivo Monitoring to In Vivo Continuous Imaging; From Single Protein Molecules to Nonbiochemical Biomarkers; NEW WAYS OF ANALYZING BIOMARKER DATA; From Single Biomarkers to Biomarker Patterns
- Modeling in Target Identification and ValidationModeling in Lead Identification and Optimization; Modeling in ADME; Use of Modeling and Simulation in Phase 1; Modeling and Simulation in Phases 2, 3, and 4; Impact of Modeling and Simulation on Drug Approvals; Oncology, a Special Case; NEXT LEVEL OF CONTRIBUTION FROM MODELING AND SIMULATION; References; 4
- Advancements in Omics Sciences; OUTLINE OF THE CHAPTER; INTRODUCTION; GENOMICS; Genomic Technologies; Microarrays; Quantitative PCR; Next-Generation Sequencing; Array-Based Comparative Genome Hybridization; Genome-Wide Association Studies