Essential chemistry for formulators of semi-solid and liquid dosages /

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Kulkarni, Vitthal S. (Autor), Shaw, Charles (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Academic Press, 2015.
Temas:
Pharmaceutical chemistry.
Drug delivery systems.
Chemistry, Pharmaceutical
Drug Delivery Systems
Chimie pharmaceutique.
Systèmes d'administration de médicaments.
Drug delivery systems
Pharmaceutical chemistry
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Essential Chemistry for Formulators of Semisolid and Liquid Dosages; Copyright; CONTENTS; PREFACE; 1
  • Introduction; 2
  • Surfactants, Lipids, and Surface Chemistry; 2.1 INTRODUCTION; 2.2 TYPES OF SURFACTANTS; 2.2.1 Surfactant Micelles; 2.2.2 Anionic Surfactants; 2.2.3 Cationic Surfactants; 2.2.4 Nonionic Surfactants; 2.3 NATURAL SURFACTANTS; 2.3.1 Lipids; 2.4 THE ROLE OF SURFACTANTS IN PHARMACEUTICAL FORMULATIONS; 2.4.1 Skin Penetration Enhancers; 2.4.2 Emulsifying Agents; 2.4.2.1 Hydrophile-Lipophile Balance (HLB) System; 2.4.3 Aerosol Formulations; 2.4.4 Surfactant Gels.
  • 2.5 SURFACE CHEMISTRY FOR PHARMACEUTICAL FORMULATIONS2.5.1 Surface and Interfacial Tension; 2.5.2 Contact Angle; 2.6 CONCLUSION; REFERENCES; 3
  • Drug Delivery Vehicles; 3.1 INTRODUCTION; 3.2 EMULSION DRUG DELIVERY SYSTEMS; 3.3 LIPOSOME DRUG DELIVERY SYSTEMS; 3.3.1 Methods of Making Liposomes; 3.4 OTHER NANODRUG DELIVERY SYSTEMS; 3.5 CONCLUSION; REFERENCES; 4
  • Formulating Creams, Gels, Lotions, and Suspensions; 4.1 INTRODUCTION; 4.2 CREAMS AND LOTIONS; 4.3 GELS, OINTMENTS, AND SUSPENSIONS; 4.4 FORMULATING WITH LIPOSOMES; 4.5 EXCIPIENTS; 4.6 CONCLUSION; REFERENCES.
  • 5
  • Use of Polymers and Thickeners in Semisolid and Liquid FormulationsBACKGROUND; 5.1 POLYMERS AS STYLING AGENTS; 5.2 POLYMERS AS CONDITIONING AGENTS; 5.2.1 Cationic Polymers; 5.2.2 Silicones; 5.2.3 Proteins; 5.3 POLYMERS AS PRESERVATIVES [3,4]; 5.4 POLYMERS AS PENETRATION ENHANCERS; 5.5 POLYMERS AS THICKENING AND SUSPENDING AGENTS [11]; 5.5.1 Emulsions; 5.5.2 Gels; 5.5.2.1 Examples of Gelling Agents; 5.5.3 Suspensions; 5.5.3.1 Examples of Suspending Agents; 5.6 CHARACTERISTICS OF COMMONLY USED THICKENING, GELLING, AND SUSPENDING AGENTS; 5.6.1 Natural Hydrocolloids; 5.6.1.1 Agar.
  • 5.6.1.2 Alginates5.6.1.3 Carrageenan; 5.6.1.4 Chitin and chitosan; 5.6.1.5 Gelatin; 5.6.1.6 Guar gum; 5.6.1.7 Gum acacia/gum arabic; 5.6.1.8 Locust bean gum; 5.6.1.9 Pectin; 5.6.1.10 Starch; 5.6.1.11 Tragacanth; 5.6.1.12 Xanthan Gum; 5.6.2 Cellulose and Derivatives; 5.6.2.1 Cellulose/Microcrystalline Cellulose (MCC); 5.6.3 Synthetic Polymers; 5.6.4 Clays; REFERENCES; 6
  • Aerosols and Nasal Sprays; 6.1 AEROSOLS; 6.1.1 Types of Formulation; 6.1.2 Typical Aerosol Excipients; 6.1.2.1 Examples of Uses and Effects of Aerosol Formulation Excipients; 6.1.3 Propellants.
  • 6.1.3.1 Numerical Designations for Fluorinated Hydrocarbon Propellants6.1.3.2 Chlorofluorocarbon (CFC) Propellants; 6.1.3.3 Hydrochlorofluorocarbon (HCFC) and Hydrofluorocarbon (HFC) Propellants; 6.1.3.4 Hydrocarbon Propellants; 6.1.3.5 Compressed Gases; 6.1.4 Particle Engineering and pMDIs; 6.1.5 Manufacturing Process; 6.2 NASAL SPRAYS; 6.2.1 Types of Formulation; 6.2.2 Typical Nasal Spray Excipients; 6.2.2.1 Examples of Uses and Effects of Nasal Spray Formulation Excipients; 6.2.3 Nasal Spray Devices; 6.2.4 Manufacturing Process; REFERENCES; 7
  • Preparation and Stability Testing.

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