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Structure to function of G protein-gated inwardly rectifying (GIRK) channels /

Annotation

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Slesinger, Paul A. (Editor ), Wickman, Kevin D. (Kevin David) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Academic Press, 2015.
Colección:International review of neurobiology.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Structure to function of G protein-gated inwardly rectifying (GIRK) channels /  |c volume editors, Paul A. Slesinger, Kevin Wickman. 
264 1 |a Amsterdam :  |b Academic Press,  |c 2015. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a International Review of Neurobiology ;  |v v. Volume 123 
588 0 |a CIP data; item not viewed. 
505 0 |a Title page -- Table of Contents -- Copyright -- Contributors -- Preface -- Chapter One: Unifying Mechanism of Controlling Kir3 Channel Activity by G Proteins and Phosphoinositides -- Abstract -- 1 Introduction -- 2 Regulation of KACh by G Proteins -- 3 Molecular Constituents of Kir3 Channels and Physiological Roles -- 4 Dependence of KACh Channel Activity on PIPs -- 5 Physiological Significance of Distinct Membrane-Delimited Signaling Mechanisms -- 6 Molecular Mechanism of PIP2 Control of Kir Channel Gating 
505 8 |a 7 Posttranslational Modification Can Control Activity Through Changes in Channelâ€"PIP2 Interactions8 The Kir3 Channel Site of Gβγ Action -- Chapter Two: The Roles of Gβγ and Gα in Gating and Regulation of GIRK Channels -- Abstract -- 1 Introduction -- 2 Interaction of Gα and Gβγ With GIRK -- 3 Roles of Gβγ and Gα in GIRK's Evoked and Basal Activity -- 4 Basal Activity of GIRKs -- 5 Multimolecular Signaling Complex and the Mechanism of GIRK Activation -- Acknowledgments -- Chapter Three: RGS Redundancy and Implications in GPCRâ€"GIRK Signaling 
505 8 |a 2 Selectivity and Permeation3 Rectification -- 4 Gating -- 5 Conclusions -- Acknowledgments -- Chapter Five: Localization and Targeting of GIRK Channels in Mammalian Central Neurons -- Abstract -- 1 Introduction -- 2 Molecular Organization and Heterogeneity of GIRK Channels -- 3 Neuroanatomical Approaches to the Study of GIRK Channel Distribution -- 4 Regional Distribution of GIRK Channel Subunits in the CNS -- 5 Cellular Distribution of GIRK Channel Subunits -- 6 Subcellular Distribution of GIRK Channel Subunits 
505 8 |a 7 Developmental Aspects of GIRK Channel Distribution8 Conclusions and Future Perspectives -- Acknowledgments -- Chapter Six: GIRK Channel Plasticity and Implications for Drug Addiction -- Abstract -- 1 Introduction -- 2 GIRK Channels in the Mesocorticolimbic System -- 3 Drug-Dependent Plasticity of GIRK Channel-Dependent Signaling -- 4 Mechanisms Underlying the Plasticity of GIRK Channel-Dependent Signaling -- 5 Concluding Thoughts and Future Directions -- Acknowledgments -- Chapter Seven: GIRK Channels: A Potential Link Between Learning and Addiction -- Abstract 
504 |a Includes bibliographical references and index. 
520 8 |a Annotation  |b A comprehensive overview of state-of-the-art research into GIRK potassium channels. It reviews current knowledge and understanding, providing a starting point for researchers and practitioners entering the field. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Potassium channels. 
650 0 |a G proteins  |x Pathophysiology. 
650 0 |a Substance abuse  |x Pathophysiology. 
650 2 |a Receptors, G-Protein-Coupled 
650 2 |a Potassium Channels 
650 6 |a Canaux à potassium. 
650 6 |a Protéines G  |x Physiopathologie. 
650 6 |a Polytoxicomanie  |x Physiopathologie. 
650 7 |a SCIENCE  |x Life Sciences  |x Biochemistry.  |2 bisacsh 
650 7 |a Substance abuse  |x Pathophysiology  |2 fast 
650 7 |a Potassium channels  |2 fast 
700 1 |a Slesinger, Paul A.,  |e editor. 
700 1 |a Wickman, Kevin D.  |q (Kevin David),  |e editor.  |1 https://id.oclc.org/worldcat/entity/E39PCjDpXqHjkpb6Ckx7yhgh73 
758 |i has work:  |a Structure to function of G protein-gated inwardly rectifying (GIRK) channels (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGHYttBtRj3vpJTdqmxcHd  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version  |z 9780128024584 
830 0 |a International review of neurobiology. 
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