Cargando…
From biosynthesis to total synthesis : strategies and tactics for natural products /
Focusing on biosynthesis, this book provides readers with approaches and methodologies for modern organic synthesis. By discussing major biosynthetic pathways and their chemical reactions, transformations, and natural products applications; it links biosynthetic mechanisms and more efficient total s...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, New Jersey :
John Wiley & Sons, Inc.,
[2016]
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
|---|---|---|---|
| 001 | EBOOKCENTRAL_ocn930875600 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
| 006 | m o d | ||
| 007 | cr ||||||||||| | ||
| 008 | 151201s2016 nju ob 001 0 eng | ||
| 010 | |a 2015047240 | ||
| 040 | |a DLC |b eng |e rda |e pn |c DLC |d OCLCF |d N$T |d EBLCP |d DG1 |d IDEBK |d YDXCP |d CDX |d TXM |d COO |d KSU |d DG1 |d UPM |d RECBK |d MERUC |d LOA |d COCUF |d DG1 |d K6U |d STF |d CCO |d PIFAG |d FVL |d VGM |d OCLCQ |d U3W |d ZCU |d OCLCQ |d WRM |d OCLCQ |d ICG |d VT2 |d AU@ |d UKMGB |d OCLCQ |d WYU |d TKN |d OCLCQ |d BRX |d DKC |d OCLCQ |d UHL |d UKAHL |d OCLCA |d OCLCQ |d OCLCO |d OCLCQ |d OCLCO |d OCLCL | ||
| 016 | 7 | |a 017782605 |2 Uk | |
| 019 | |a 1055365534 |a 1066623990 |a 1081286490 |a 1113627476 |a 1124463685 |a 1148139223 | ||
| 020 | |a 9781118753637 |q (ePub) | ||
| 020 | |a 1118753631 |q (ePub) | ||
| 020 | |a 9781118753569 |q (Adobe PDF) | ||
| 020 | |a 1118753569 |q (Adobe PDF) | ||
| 020 | |a 1118751736 |q (cloth) | ||
| 020 | |a 9781118751732 |q (cloth) | ||
| 020 | |z 9781118751732 |q (cloth) | ||
| 020 | |z 9781118754085 | ||
| 020 | |z 1118754085 | ||
| 029 | 1 | |a AU@ |b 000056765224 | |
| 029 | 1 | |a CHNEW |b 000944958 | |
| 029 | 1 | |a CHVBK |b 480251967 | |
| 029 | 1 | |a DEBBG |b BV044060808 | |
| 029 | 1 | |a DEBSZ |b 485063662 | |
| 029 | 1 | |a UKMGB |b 017782605 | |
| 035 | |a (OCoLC)930875600 |z (OCoLC)1055365534 |z (OCoLC)1066623990 |z (OCoLC)1081286490 |z (OCoLC)1113627476 |z (OCoLC)1124463685 |z (OCoLC)1148139223 | ||
| 037 | |a 9781118753637 |b Wiley | ||
| 042 | |a pcc | ||
| 050 | 0 | 0 | |a QD262 |
| 072 | 7 | |a SCI |x 007000 |2 bisacsh | |
| 082 | 0 | 0 | |a 572/.45 |2 23 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a From biosynthesis to total synthesis : |b strategies and tactics for natural products / |c edited by Alexandros L. Zografos. |
| 264 | 1 | |a Hoboken, New Jersey : |b John Wiley & Sons, Inc., |c [2016] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record and CIP data provided by publisher. | |
| 520 | |a Focusing on biosynthesis, this book provides readers with approaches and methodologies for modern organic synthesis. By discussing major biosynthetic pathways and their chemical reactions, transformations, and natural products applications; it links biosynthetic mechanisms and more efficient total synthesis. - Describes four major biosynthetic pathways (acetate, mevalonate, shikimic acid, and mixed pathways and alkaloids) and their related mechanisms- Covers reactions, tactics, and strategies for chemical transformations, linking biosynthetic processes and total synthesis- Includes strategies for optimal synthetic plans and introduces a modern molecular approach to natural product synthesis and applications- Acts as a key reference for industry and academic readers looking to advance knowledge in classical total synthesis, organic synthesis, and future directions in the field. | ||
| 505 | 0 | |a Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- Chapter 1 From Biosyntheses to Total Syntheses: An Introduction -- 1.1 FROM PRIMARY TO SECONDARY METABOLISM: THE KEY BUILDING BLOCKS -- 1.1.1 Definitions -- 1.1.2 Energy Supply and Carbon Storing at the Early Stage of Metabolisms -- 1.1.3 Glucose as a Starting Material Toward Key Building Blocks of the Secondary Metabolism -- 1.1.4 Reactions Involved in the Construction of Secondary Metabolites -- 1.1.5 Secondary Metabolisms. | |
| 505 | 8 | |a 1.2 FROM BIOSYNTHESIS TO TOTAL SYNTHESIS: STRATEGIES TOWARD THE NATURAL PRODUCT CHEMICAL SPACE -- 1.2.1 The Chemical Space of Natural Products -- 1.2.2 The Biosynthetic Pathways as an Inspiration for Synthetic Challenges -- 1.2.3 The Science of Total Synthesis -- 1.2.4 Conclusion: A Journey in the Future of Total Synthesis -- REFERENCES -- SECTION I ACETATE BIOSYNTHETIC PATHWAY -- Chapter 2 Polyketides -- 2.1 POLYKETIDE BIOSYNTHESIS -- 2.1.1 Introduction -- 2.1.2 Assembly of Acetate/Malonate-Derived Metabolites -- 2.1.3 Classification of Polyketide Biosynthetic Machineries -- 2.1.4 Conclusion. | |
| 505 | 8 | |a Chapter 3 FATTY ACIDS AND THEIR DERIVATIVES -- 3.1 INTRODUCTION -- 3.2 BIOSYNTHESIS -- 3.2.1 Fatty Acids and Lipids -- 3.2.2 Polyunsaturated Fatty Acids -- 3.2.3 Mediated Oxidations of (S} (B-3 and (S} (B-6 Polyunsaturated Fatty Acids -- 3.3 SYNTHESIS OF (S} (B-3 AND (S} (B-6 ALL-Z POLYUNSATURATED FATTY ACIDS -- 3.3.1 Synthesis of Polyunsaturated Fatty Acids by the Wittig Reaction or by the Polyyne Semihydrogenation -- 3.3.2 Synthesis of Polyunsaturated Fatty Acids via Cross Coupling Reactions -- 3.4 APPLICATIONS IN TOTAL SYNTHESIS OF POLYUNSATURATED FATTY ACIDS -- 3.4.1 Palladium-Catalyzed Cross Coupling Reactions. | |
| 505 | 8 | |a 3.4.2 Biomimetic Transformations of Polyunsaturated Fatty Acids -- 3.4.3 Landmark Total Syntheses -- 3.4.4 Synthesis of Leukotriene B5 -- 3.5 CONCLUSION -- ACKNOWLEDGMENTS -- References -- Chapter 4 Polyethers -- 4.1 INTRODUCTION -- 4.2 BIOSYNTHESIS -- 4.2.1 Ionophore Antibiotics -- 4.2.2 Marine Ladder Toxins -- 4.2.3 Annonaceous Acetogenins and Terpene Polyethers -- 4.3 EPOXIDE REACTIVITY AND STEREOSELECTIVE SYNTHESIS -- 4.3.1 Regiocontrol in Epoxide-Opening Reactions -- 4.3.2 Stereoselective Epoxide Synthesis -- 4.4 APPLICATIONS TO TOTAL SYNTHESIS -- 4.4.1 Acid-Mediated Transformations. | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Organic compounds |x Synthesis. | |
| 650 | 0 | |a Biosynthesis. | |
| 650 | 6 | |a Composés organiques |x Synthèse. | |
| 650 | 6 | |a Biosynthèse. | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biochemistry. |2 bisacsh | |
| 650 | 7 | |a Biosynthesis |2 fast | |
| 650 | 7 | |a Organic compounds |x Synthesis |2 fast | |
| 700 | 1 | |a Zografos, Alexandros L., |e editor. | |
| 758 | |i has work: |a From biosynthesis to total synthesis (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGgbfq34G687d6bdW9vmBP |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |t From biosynthesis to total synthesis. |d Hoboken, New Jersey : John Wiley & Sons, Inc., [2016] |z 9781118751732 |w (DLC) 2015037375 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=4454410 |z Texto completo |
| 938 | |a Coutts Information Services |b COUT |n 32691865 | ||
| 938 | |a EBL - Ebook Library |b EBLB |n EBL4454410 | ||
| 938 | |a EBSCOhost |b EBSC |n 1203168 | ||
| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n cis32691865 | ||
| 938 | |a Recorded Books, LLC |b RECE |n rbeEB00668959 | ||
| 938 | |a YBP Library Services |b YANK |n 12900640 | ||
| 938 | |a YBP Library Services |b YANK |n 11225754 | ||
| 938 | |a Askews and Holts Library Services |b ASKH |n AH30143972 | ||
| 994 | |a 92 |b IZTAP | ||