Toxicological Effects of Methylmercury.

Annotation

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Staff, National Research Council
Otros Autores: Methylmercury, Committee on the Toxicological Effects of, Staff, Board on Environmental Studies and Toxicology
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington : National Academies Press, 2000.
Colección:Online access: National Academy of Sciences National Academies Press.
Online access: NCBI NCBI Bookshelf.
Temas:
Methylmercury > Toxicology.
Methylmercury Compounds > toxicity
Mercury > toxicity
Méthylmercure > Toxicologie.
Methylmercury > Toxicology
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Toxicological Effects of Methylmercury
  • Copyright
  • PREFACE
  • Contents
  • EXECUTIVE SUMMARY
  • THE CHARGE TO THE COMMITTEE
  • THE COMMITTEE'S APPROACH TO ITS CHARGE
  • THE COMMITTEE'S EVALUATION
  • Health Effects of Methylmercury
  • Determination of the Critical Study for the RfD
  • Estimation of Dose and Biological Variability
  • Modeling the Dose-Response Relationships
  • Public-Health Implications
  • RESEARCH NEEDS
  • RECOMMENDATIONS
  • 1 INTRODUCTION
  • SOURCES OF HG
  • FATE AND TRANSPORT
  • HEALTH EFFECTS
  • EXPOSURE EVENTS AND STUDIES
  • SUMMARY OF RISK ASSESSMENTS FOR MEHGSCIENTIFIC CONTROVERSIES AND SOURCES OF UNCERTAINTY
  • ORGANIZATION OF THE REPORT
  • REFERENCES
  • 2 CHEMISTRY, EXPOSURE, TOXICOKINETICS, AND TOXICODYNAMICS
  • PHYSICAL AND CHEMICAL PROPERTIES
  • METHODS OF CHEMICAL ANALYSIS
  • EXPOSURES TO MEHG IN THE U.S. POPULATION
  • TOXICOKINETICS
  • Absorption and Distribution
  • Methylmercury
  • Dimethylmercury
  • Elemental Mercury
  • Inorganic Mercury
  • Biotransformation
  • Excretion
  • MOBILIZATION OF BODY HG
  • CHEMICAL FORMS OF HG IN TOXICITY
  • TOXIC EFFECTS AND TARGET ORGANSBIOCHEMICAL MECHANISMS OF TOXICITY
  • SUMMARY AND CONCLUSIONS
  • RECOMMENDATIONS
  • REFERENCES
  • 3 BIOLOGICAL VARIABILITY
  • AGE-RELATED SUSCEPTIBILITY
  • GENDER DIFFERENCES
  • GENETICS
  • MECHANISMS OF NUTRITIONAL INFLUENCE ON MEHG HEALTH EFFECTS
  • Dietary Interactions and Confounding
  • Selenium
  • Garlic
  • Omega-3 Fatty Acids
  • Protein
  • Alcohol
  • Other Foods That Might Influence Hg Uptake
  • Vitamin E
  • Nutrient Enhancement of Toxicity
  • Beneficial Effects of Fish Consumption
  • TOXICOKINETIC VARIABILITY
  • CONCLUSIONSRECOMMENDATIONS
  • REFERENCES
  • 4 DOSE ESTIMATION
  • DIETARY ASSESSMENT
  • BIOMARKERS OF EXPOSURE
  • Methylmercury in Blood
  • Methylmercury in Hair
  • Comparison of Biomarkers of Exposure
  • ANALYTICAL ERROR IN BIOMARKER MEASUREMENTS
  • EXPOSURE AND DOSE ASSESSMENT IN THE SEYCHELLES, FAROE ISLANDS, AND NEW ZEALAND STUDIES
  • SUMMARY AND CONCLUSIONS
  • RECOMMENDATIONS
  • REFERENCES
  • 5 HEALTH EFFECTS OF METHYLMERCURY
  • CARCINOGENICITY
  • Human Studies
  • Animal Studies
  • GENOTOXICITY
  • Human Studies
  • Animal Studies
  • In Vitro StudiesIMMUNOTOXICITY
  • Human Studies
  • Animal Studies
  • Effects on the Adult Immune System
  • Effects on the Developing Immune System
  • In Vitro Studies
  • Autoimmune Response
  • Human Studies
  • Animal Studies
  • REPRODUCTIVE EFFECTS
  • Human Studies
  • Animal Studies
  • RENAL TOXICITY
  • Human Studies
  • Animal Studies
  • CARDIOVASCULAR EFFECTS
  • Human Studies
  • Animal Studies
  • HEMATOLOGICAL EFFECTS
  • DEVELOPING CENTRAL-NERVOUS-SYSTEM TOXICITY
  • Human Studies
  • High-Dose Poisonings
  • Poisoning Episode in Japan

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