Drinking Water and Health.
Clasificación: | Libro Electrónico |
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Autor principal: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Washington :
National Academies Press,
1900.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ""Drinking Water and Health""; ""Copyright""; ""List of Participants""; ""Preface""; ""Contents""; ""1 Executive Summary ""; ""DEVELOPMENTAL TOXICITY""; ""REPRODUCTIVE TOXICITY""; ""NEUROTOXICITY""; ""CARCINOGENESIS""; ""DOSE-ROUTE EXTRAPOLATION""; ""THE USE OF EPIDEMIOLOGICAL STUDIES IN RISK ASSESSMENTS""; ""A FRAMEWORK FOR RISK ASSESSMENT""; ""TOXICOLOGICAL ASSESSMENT OF 14 COMPOUNDS""; ""2 Developmental Effects of Chemical Contaminants ""; ""INFLUENCE OF TIME OF EXPOSURE""; ""PATTERNS OF DOSE RESPONSE IN LABORATORY ANIMAL STUDIES""; ""EXTRAPOLATION OF ANIMAL DATA TO HUMANS""
- ""Spectrum of End Points""""Concordance of Results from Animal and Human Studies""; ""INTERPRETATION OF ANIMAL DATA""; ""Quality and Quantity of Data""; ""Relationship between Maternal and Developmental Toxicity""; ""Selection of the NOEL/LOEL""; ""RISK ASSESSMENT""; ""Quantitative Assessment of Developmental Toxicity""; ""Selection of the Safety Factor""; ""REFERENCES""; ""3 Reproductive Toxicology ""; ""SUSCEPTIBILITY OF THE NONPREGNANT FEMALE TO REPRODUCTIVE IMPAIRMENT""; ""Maturation of the Female Reproductive System""; ""Oocyte Toxicity""; ""Effects of Radiation on Oogenesis""
- ""Effects of Xenobiotic Compounds on Oogenesis""""Polycyclic Aromatic Hydrocarbons (PAHs)""; ""Antineoplastic Agents""; ""Alterations in Reproductive Endocrinology""; ""Endocrine Alterations in the Perinatal Period""; ""Cns-Mediated Endocrine Alterations in the Adult""; ""Test Systems for Detecting Female Infertility""; ""SUSCEPTIBILITY OF THE MALE TO REPRODUCTIVE IMPAIRMENT""; ""Maturation of the Male Reproductive System""; ""Sperm Toxicity""; ""Effects of Radiation on Spermatogenesis""; ""Test Systems for Evaluating Male Reproductive Toxicity in Laboratory Animals""; ""Entry-Level Testing""
- ""Human Test Systems""""Sperm Morphology""; ""Sperm Motility""; ""Semen Analysis""; ""Sperm Concentration""; ""Sperm Chromosome Complement""; ""Sperm-Cervical Mucus Interaction""; ""Sperm-Oocyte Interaction""; ""Examination of Seminal Fluid""; ""GERM CELL MUTAGENESIS IN MALES AND FEMALES""; ""Test Systems for Germ Cell Mutations""; ""Dominant Lethal Test""; ""Heritable Translocation Test""; ""Specific Locus Test""; ""RISK ASSESSMENT IN REPRODUCTIVE TOXICOLOGY""; ""APPENDIX: DETAILS OF TEST PROTOCOLS FOR REPRODUCTIVE TOXICOLOGY TESTING""; ""MULTIGENERATION TEST""
- ""FERTILITY ASSESSMENT BY CONTINUOUS BREEDING""""SEGMENT I STUDIES: GENERAL FERTILITY AND REPRODUCTIVE PERFORMANCE""; ""TIME OF VAGINAL OPENING IN THE RAT PUP""; ""UTERINE EPITHELIAL HYPERTROPHY""; ""PRIMORDIAL OOCYTE DESTRUCTION IN JUVENILE MICE""; ""SPERM PRODUCTION RATES IN RATS""; ""ASSESSMENT OF EPIDIDYMAL SPERM NUMBERS AND TRANSIT TIMES""; ""ASSESSMENT OF SPERM MOTILITY""; ""HISTOLOGICAL EVALUATION OF THE TESTIS""; ""REFERENCES""; ""4 Neurotoxic Effects ""; ""THE HUMAN NERVOUS SYSTEM IN HEALTH AND DISEASE""; ""Gross Structure and Function""; ""Cellular Structure and Function""