Drinking Water and Health, Volume 9 : Selected Issues in Risk Assessment.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Staff, National Research Council
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington : National Academies Press, 1900.
Temas:
Drinking water > Contamination.
Drinking water > Health aspects > United States.
Eau potable > Contamination.
Drinking water > Contamination
Drinking water > Health aspects
United States
Acceso en línea:Texto completo
Tabla de Contenidos:
  • ""Drinking Water and Health""; ""Copyright""; ""PREFACE""; ""Contents""; ""PART I DNA ADDUCTS ""; ""Executive Summary""; ""1 Biologic Significance of DNA Adducts and Protein Adducts ""; ""DYNAMICS OF DNA-ADDUCT FORMATION AND REMOVAL""; ""DNA-Adduct Formation Rates""; ""DNA Repair""; ""SITE RELEVANCE""; ""Alkylation""; ""Base Mispairing""; ""Hydrolysis""; ""Phosphate Adducts""; ""Cross-Links""; ""DNA ADDUCTS AND TOXIC EFFECTS""; ""In Vitro Short-Term Bioassay""; ""In Vivo Germ Cell Mutation""; ""Tumorigenesis in Animal Models""; ""Single-Dose Exposures of Animals""
  • ""Chronic Exposures of Animals""""Studies in Humans""; ""PROTEIN ADDUCTS""; ""SUMMARY""; ""References""; ""2 DNA-Adduct Technology ""; ""TECHNIQUES FOR DETECTING DNA ADDUCTS""; ""Chromatographic and Spectrometric Methods""; ""Liquid Chromatography/Mass Spectrometry (LC/MS)""; ""High-Performance Liquid Chromatography (HPLC)""; ""Atomic-Absorption Spectrometry (AAS)""; ""Tandem Mass Spectrometry (MS/MS)""; ""Fluorescence Line-Narrowing Spectrometry (FLNS)""; ""Ultraviolet Radiation/High-Performance Liquid Chromatography (UV/HPLC)""
  • ""Gas Chromatography/Electron Capture Negative Ion Mass Spectrometry (GC/ECNIMS)""""Quantitative Immunoassays""; ""Radioimmunoassay (RIA)""; ""Enzyme-Linked Immunosorbent Assay (ELISA)""; ""Ultrasensitive Enzymatic Radioimmunoassay (USERIA)""; ""Immunohistochemical Techniques""; ""32P-Postlabeling Technique""; ""TECHNIQUES FOR DETECTING PROTEIN ADDUCTS""; ""SENSITIVITY AND SPECIFICITY""; ""APPLICATIONS OF DNA ADDUCT TECHNOLOGY""; ""General Utility in Risk Assessment""; ""Epidemiology and Human Monitoring""; ""References""; ""3 Conclusions and Recommendations ""
  • ""Appendix A Drinking Water Contaminant Candidates for Development of Baseline Data on Formation of DNA Adducts""""CONTAMINANTS THAT DEFINITELY FORM DNA ADDUCTS""; ""Acrylamide""; ""Benzo[α]Pyrene (Bαp)""; ""Chromium""; ""Dibromochloropropane (DBCP)""; ""Ethylene Dibromide (EDB)""; ""A CONTAMINANT THAT PROBABLY FORMS DNA ADDUCTS""; ""Trichlorfon""; ""CONTAMINANTS THAT POSSIBLY FORM DNA ADDUCTS""; ""Diallate""; ""Sulfallate""; ""Chloropropanes And Chloropropenes""; ""Di(2-Ethylhexyl) Phthalate (DEHP) And Mono(2-Ethylhexyl) Phthalate (MEHP)""
  • ""CONTAMINANTS ON WHICH THERE IS NO EVIDENCE OF DNA-ADDUCT FORMATION""""Arsenic""; ""Nitrofen""; ""Pentachlorophenol""; ""REFERENCES""; ""Glossary""; ""Biographical Sketches""; ""SUBCOMMITTEE ON DNA ADDUCTS""; ""PART II MIXTURES ""; ""Executive Summary""; ""APPROACHES FOR PROBLEM RESOLUTION""; ""GROUPING CHEMICALS FOR ESTIMATION OF COMBINED RISK""; ""USING PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING""; ""STATISTICAL APPROACHES FOR REDUCING EXPERIMENTATION (RESPONSE-SURFACE DESIGNS AND FRACTIONAL FACTORIALS)""; ""ASSESSING EXPOSURE""; ""APPLICATIONSâ€?PROBLEMS OF EXPOSURE""

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