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020 |a 9780309596985 
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020 |a 0309064414 
020 |a 9780309064415 
029 1 |a DEBBG  |b BV044107385 
035 |a (OCoLC)923265549  |z (OCoLC)994494876 
050 4 |a QR201.S6.A85 1999eb 
082 0 4 |a 616.912 
049 |a UAMI 
100 1 |a Staff, Institute of Medicine. 
245 1 0 |a Assessment of Future Scientific Needs for Live Variola Virus. 
260 |a Washington :  |b National Academies Press,  |c 1999. 
300 |a 1 online resource (126 pages) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 0 |a The compass series Assessment of future scientific needs for live variola virus 
588 0 |a Print version record. 
505 0 |a Assessment of Future Scientific Needs for Live Variola Virus -- Copyright -- Preface -- Acknowledgments -- REVIEWERS -- Contents -- Executive Summary -- SCOPE -- SCIENTIFIC NEEDS FOR LIVE AND REPLICATION-DEFECTIVE VARIOLA VIRUS -- OVERALL CONCLUSIONS -- Part I Introduction -- 1 Introduction -- BACKGROUND -- CONTEMPORARY CONTEXT -- SCOPE -- SCIENTIFIC NEEDS FOR VARIOLA VIRUS -- ORGANIZATION OF THIS REPORT -- Part II Smallpox and Its Control -- 2 Variola Virus and Other Orthopoxviruses -- GENERAL ATTRIBUTES OF ORTHOPOXVIRUSES 
505 8 |a POXVIRUS REPLICATIONPROPERTIES OF SPECIFIC ORTHOPOXVIRUSES -- 3 Clinical Features of Smallpox -- ENTRY AND INFECTION -- DISSEMINATION -- THE RASH -- LESIONS OF THE MUCOUS MEMBRANES -- EFFECTS ON OTHER ORGANS -- IMMUNE RESPONSE -- IMMUNITY AGAINST SMALLPOX -- 4 Epidemiology -- CHARACTERISTICS OF HISTORICAL OUTBREAKS -- LIKELY CHARACTERISTICS OF FUTURE SMALLPOX OUTBREAKS -- CONTROL STRATEGIES -- 5 Variola Virus Stocks Following Eradication of Smallpox -- ESTABLISHMENT OF INTERNATIONAL REPOSITORIES 
505 8 |a DECISION BY THE WORLD HEALTH ASSEMBLY TO DESTROY VARIOLA VIRUS STOCKSU.S. RESEARCH ON SMALLPOX -- RESEARCH AT CDC AND USAMRIID -- Part III Scientific Needs for Variola Virus -- 6 Development of Antiviral Agents -- IN VITRO ASSAYS -- ANIMAL MODELS -- 7 Development of Vaccines -- CURRENT STATUS OF VACCINIA VACCINE PREPARATIONS -- EVALUATION OF VACCINIA VACCINE DERIVED FROM TISSUE CULTURE -- EVALUATION OF NOVEL VACCINES -- 8 Detection and Diagnosis -- ENVIRONMENTAL DETECTION -- DIAGNOSIS OF INFECTION -- ALTERNATIVES TO LIVE VIRUS -- 9 Bioinformatics 
505 8 |a VARIABILITY OF VARIOLA VIRUSPOTENTIAL DEVELOPMENTS -- 10 Understanding of the Biology of Variola Virus -- VIRUS-CELL INTERACTIONS -- VIRUS-HOST INTERACTIONS -- 11 Research on the Expressed Protein Products of Variola -- SYNTHESIS OF VARIOLA PROTEINS -- POTENTIAL UTILITY OF VARIOLA PROTEINS -- Part IV Findings -- 12 Summary and Conclusions -- THE BROADER CONTEXT -- SCIENTIFIC NEEDS FOR LIVE VARIOLA VIRUS -- OVERALL CONCLUSIONS -- References -- Appendix A Glossary -- Appendix B Acronyms -- Appendix C Committee and Staff Biographies -- Staff 
546 |a English. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Smallpox  |x Research. 
650 0 |a Smallpox  |x Prevention. 
650 0 |a Smallpox vaccine  |x Cultures and culture media. 
650 0 |a Virology. 
650 0 |a Science. 
650 0 |a Physical sciences. 
650 0 |a Virus diseases. 
650 0 |a DNA viruses. 
650 0 |a Diseases. 
650 0 |a Viruses. 
650 0 |a Research. 
650 2 |a Investigative Techniques 
650 2 |a Science 
650 2 |a Orthopoxvirus 
650 2 |a Poxviridae Infections 
650 2 |a DNA Virus Infections 
650 2 |a Chordopoxvirinae 
650 2 |a Analytical, Diagnostic and Therapeutic Techniques and Equipment 
650 2 |a Natural Science Disciplines 
650 2 |a Virus Diseases 
650 2 |a Disciplines and Occupations 
650 2 |a Poxviridae 
650 2 |a DNA Viruses 
650 2 |a Disease 
650 2 |a Viruses 
650 2 |a Vertebrate Viruses 
650 2 |a Organisms 
650 2 |a Variola virus 
650 2 |a Research 
650 2 |a Smallpox 
650 2 |a Containment of Biohazards 
650 2 |a Virology 
650 6 |a Variole  |x Recherche. 
650 6 |a Variole  |x Prévention. 
650 6 |a Vaccin antivariolique  |x Cultures et milieux de culture. 
650 6 |a Virologie. 
650 6 |a Sciences. 
650 6 |a Sciences physiques. 
650 6 |a Maladies à virus. 
650 6 |a Virus à ADN. 
650 6 |a Maladies. 
650 6 |a Virus. 
650 6 |a Recherche. 
650 7 |a sciences (philosophy)  |2 aat 
650 7 |a physical sciences.  |2 aat 
650 7 |a research (function)  |2 aat 
650 7 |a science (modern discipline)  |2 aat 
650 7 |a Viruses  |2 fast 
650 7 |a Virus diseases  |2 fast 
650 7 |a Science  |2 fast 
650 7 |a Research  |2 fast 
650 7 |a Physical sciences  |2 fast 
650 7 |a DNA viruses  |2 fast 
650 7 |a Diseases  |2 fast 
650 7 |a Smallpox  |x Prevention  |2 fast 
650 7 |a Virology  |2 fast 
776 0 8 |i Print version:  |a Staff, Institute of Medicine.  |t Assessment of Future Scientific Needs for Live Variola Virus.  |d Washington : National Academies Press, ©1900  |z 9780309064415 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=3376680  |z Texto completo 
938 |a Askews and Holts Library Services  |b ASKH  |n AH36567540 
938 |a EBL - Ebook Library  |b EBLB  |n EBL3376680 
994 |a 92  |b IZTAP