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20240329122006.0 |
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151010s1900 dcu o 000 0 eng d |
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|a EBLCP
|b eng
|e pn
|c EBLCP
|d OCLCQ
|d MERUC
|d ZCU
|d ICG
|d OCLCO
|d OCLCF
|d OCLCQ
|d OCLCO
|d OCLCQ
|d LVT
|d DKC
|d AU@
|d OCLCQ
|d OCLCO
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|a 9780309597609
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|a 0309597609
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|a DEBBG
|b BV044107245
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|a (OCoLC)923264562
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|a RC347.5.E5
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|a 616.07
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|a UAMI
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|a Staff, National Research Council.
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|a Environmental Neurotoxicology.
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| 260 |
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|a Washington :
|b National Academies Press,
|c 1900.
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| 300 |
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|a 1 online resource (166 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a ""Environmental Neurotoxicology""; ""Copyright""; ""Preface""; ""Contents""; ""Executive Summary""; ""MAGNITUDE OF THE PROBLEM""; ""NEUROTOXICITY TESTING""; ""SURVEILLANCE AND EPIDEMIOLOGIC STUDIES IN ENVIRONMENTAL NEUROTOXICOLOGY""; ""BIOLOGIC MARKERS IN ENVIRONMENTAL NEUROTOXICOLOGY""; ""NEUROTOXICITY RISK ASSESSMENT""; ""1 Introduction: Defining the Problem of Neurotoxicity""; ""NEUROLOGIC RESPONSES TO ENVIRONMENTAL TOXICANTS""; ""MAGNITUDE OF THE PROBLEM OF NEUROTOXICITY""; ""DETECTION AND CONTROL OF EXPOSURE TO NEUROTOXICANTS""; ""SCOPE OF THIS REPORT""
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| 505 |
8 |
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|a ""2 Biologic Basis of Neurotoxicity""""CELLULAR ANATOMY AND PHYSIOLOGY""; ""Structure of the Neuron""; ""The Nerve Impulse""; ""Synaptic Transmission""; ""Synaptic Messengers""; ""GENERAL ASPECTS OF NERVOUS SYSTEM STRUCTURE AND FUNCTION""; ""Metabolism""; ""Blood-Brain Barrier""; ""Development""; ""Plasticity""; ""Trophic Interactions""; ""VULNERABILITY OF THE NERVOUS SYSTEM TO CHEMICAL TOXICANTS""; ""Complexity of Structural and Functional Integration""; ""Limitations on Repair""; ""Accessibility to Lipid-Soluble Toxicants""; ""Dependence on Glucose""; ""Axonal Transport""
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| 505 |
8 |
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|a ""Synaptic Transmission""""Ion Channels""; ""EXAMPLES OF NEUROTOXIC MECHANISMS""; ""Pyrethroids""; ""γ-Diketones""; ""MPTP""; ""SUMMARY""; ""3 Biologic Markers in Neurotoxicology""; ""CONCEPTS AND DEFINITIONS""; ""Biologic Markers of Exposure""; ""Biologic Markers of Effect""; ""Biologic Markers of Susceptibility""; ""VALIDATION OF BIOLOGIC MARKERS""; ""USE OF BIOLOGIC MARKERS IN RISK ASSESSMENT""; ""SUMMARY""; ""4 Testing for Neurotoxicity""; ""APPROACH TO NEUROTOXICITY TESTING""; ""Difficulties in Neurotoxicity Testing""; ""The Testing Strategy""
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| 505 |
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|a ""Characteristics of Tests Useful for Screening""""Application of the Screen and Later Tiers""; ""CURRENT METHODS BASED ON STRUCTURE-ACTIVITY RELATIONSHIPS""; ""CURRENT IN VITRO PROCEDURES""; ""Biochemical Assays""; ""Tissue Culture""; ""Plausibility of an In Vitro Screening Battery""; ""CURRENT IN VIVO PROCEDURES""; ""Behavioral Assessment""; ""Functional Observational Batteries""; ""Motor Activity""; ""Schedule-Controlled Operant Behavior""; ""Specialized Tests of Neurologic Function""; ""Motor Function""; ""Sensory Function""; ""Learning and Memory""; ""Neurophysiologic Procedures""
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| 505 |
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|a ""Nerve-Conduction Studies""""Sensory Evoked Potentials""; ""Electroencephalography""; ""Neurochemical Procedures""; ""Neuroendocrine Interactions""; ""Neuropathology""; ""Imaging Procedures""; ""Modifying Variables""; ""Age at Exposure""; ""Age at Testing""; ""Sex""; ""Genetic Differences""; ""CURRENT REGULATORY APPROACHES""; ""STRATEGIES FOR IMPROVED NEUROTOXICITY TESTING""; ""Screening""; ""Validation""; ""Priority-Setting and Implementation""; ""Research Needs""; ""5 Surveillance to Prevent Neurotoxicity in Humans""; ""Need for Surveillance""; ""NEUROBEHAVIOURAL TEST BATTERIES""
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| 500 |
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|a ""Current exposure surveillance efforts""
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| 590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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| 650 |
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0 |
|a Neurotoxicology.
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| 650 |
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0 |
|a Environmental monitoring.
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| 650 |
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0 |
|a Health risk assessment.
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| 650 |
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2 |
|a Environmental Monitoring
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| 650 |
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2 |
|a Health Status Indicators
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| 650 |
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6 |
|a Neurotoxicologie.
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| 650 |
|
6 |
|a Environnement
|x Surveillance.
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| 650 |
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6 |
|a Risques pour la santé
|x Évaluation.
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| 650 |
|
7 |
|a Environmental monitoring
|2 fast
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| 650 |
|
7 |
|a Health risk assessment
|2 fast
|
| 650 |
|
7 |
|a Neurotoxicology
|2 fast
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| 776 |
0 |
8 |
|i Print version:
|a Staff, National Research Council.
|t Environmental Neurotoxicology.
|d Washington : National Academies Press, ©1900
|z 9780309045315
|
| 856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=3376537
|z Texto completo
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| 938 |
|
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|a ProQuest Ebook Central
|b EBLB
|n EBL3376537
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| 994 |
|
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|a 92
|b IZTAP
|
