Biologic Markers in Urinary Toxicology.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Staff, National Research Council
Otros Autores: Toxico, Subcommittee on Biologic Markers in Urinary
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington : National Academies Press, 1995.
Colección:Online access: National Academy of Sciences National Academies Press.
Online access: NCBI NCBI Bookshelf.
Temas:
Nephrotoxicology > Treatment > Diseases.
Biochemical markers > Toxicology.
Genitourinary organs.
Tumor markers.
Xenobiotics.
Drugs.
Diseases.
Body fluids.
Anatomy.
Genitourinary organs > Diseases.
Urine.
Biochemical markers.
Biological products.
Pharmaceutical Preparations
Female Urogenital Diseases and Pregnancy Complications
Disease
Body Fluids
Biological Factors
Chemicals and Drugs
Fluids and Secretions
Anatomy
Xenobiotics
Female Urogenital Diseases
Urine
Biomarkers
Male Urogenital Diseases
Urogenital System
Biomarkers, Tumor
Néphrotoxicité > Traitement > Maladies.
Marqueurs biologiques > Toxicologie.
Appareil urogénital.
Marqueurs tumoraux.
Xénobiotiques.
Médicaments.
Maladies.
Liquides organiques.
Produits biologiques.
Anatomie.
Appareil urogénital > Maladies.
Marqueurs biologiques.
anatomy.
urine.
Genitourinary organs > Diseases
Drugs
Diseases
Body fluids
Biochemical markers
Genitourinary organs
Tumor markers
Acceso en línea:Texto completo
Tabla de Contenidos:
  • BIOLOGIC MARKERS IN URINARY TOXICOLOGY
  • COPYRIGHT
  • OTHER RECENT REPORTS OF THE BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY
  • PREFACE
  • CONTENTS
  • EXECUTIVE SUMMARY
  • EFFECTS OF TOXIC EXPOSURE OF THE URINARY TRACT
  • BIOLOGIC MARKERS OF SUSCEPTIBILITY AND EXPOSURE
  • BIOLOGIC MARKERS OF EFFECT
  • BIOLOGIC MARKERS IN EXTRAPOLATION
  • NEW TECHNOLOGIES
  • THE SUBCOMMITTEE'S RECOMMENDATIONS
  • General
  • The Kidney
  • The Bladder
  • The Prostate
  • Biologic Markers of Exposure and Susceptibility
  • Biologic Markers of Effect
  • Use of Biologic Markers in ExtrapolationNew Technologies
  • 1 INTRODUCTION
  • BIOLOGIC MARKERS
  • Markers of Exposure
  • Markers of Effect
  • Markers of Susceptibility
  • VALIDITY OF BIOLOGIC MARKERS
  • ETHICAL ISSUES
  • STRUCTURE OF THE REPORT
  • 2 TOXIC EXPOSURE OF THE URINARY TRACT
  • THE URINARY TRACT
  • Renal Blood Flow
  • Glomerular Filtration
  • Tubular Reabsorption and Secretion
  • Hormonal Action
  • MECHANISMS OF RENAL TOXICITY
  • Susceptibility to Injury
  • Direct Toxic Effects
  • Renal Vascular Injury
  • Glomerular Capillary Injury
  • Renal Tubular-Cell InjuryIndirect Toxic Effects
  • Immunopathologic Mechanisms
  • Xenobiotic Metabolism
  • Necrosis and Apoptosis
  • HOST FACTORS IN RENAL TOXICITY
  • Changes with Renal Growth and Aging
  • Changes with Diet
  • Influence of Pre-existing Renal Function
  • Nephron Number at Birth
  • Acute Renal Disease
  • Chronic Renal Disease
  • Physiologic Responses to Renal Injury
  • Physiologic Changes with Compensatory Hypertrophy
  • Factors Associated with Progressive Low of Renal Function
  • CLINICAL EFFECTS OF CHEMICAL EXPOSURE ON THE KIDNEY
  • Acute Renal FailureTubulointestitial Nephritis
  • Chronic Glomerulonephritis
  • Rapidly Progressive Glomerulonephritis
  • Nephrotic Syndrome
  • Hypertension
  • CANCER OF THE BLADDER, KIDNEY, AND PROSTATE
  • Tumor-Suppressor Genes, Oncogenes, and Growth Factors
  • Cancer of the Bladder
  • Cancer of the Kidney
  • Cancer of the Prostate
  • Interstitial Cystitis
  • ANIMAL MODELS OF INTERSTITIAL CYSTITIS
  • SUMMARY
  • 3 BIOLOGIC MARKETS OF SUSCEPTIBILITY AND EXPOSURE
  • POPULATIONS AT RISK
  • Hereditary Susceptibility to Nephrotoxicity
  • Nutrition
  • Socioeconomic FactorsAge
  • Coexisting Chronic Disease
  • Addictive Behavior and Recreational Drug Use
  • Occupational or Environmental Exposure
  • MARKERS OF SUSCEPTIBILITY
  • Modifying Factors of Susceptibility
  • Parenchymal Renal Disease
  • Cytochrome P-450-Dependent Activation of Nephrotoxicants
  • Prostaglandin H Synthase-Dependent Activation of Nephrotoxicants
  • Glutathione-Dependent Activation of Nephrotoxicants
  • Extrarenal Conjugation and Interorgan Metabolism

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