The essential guide to N-of-1 trials in health /

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N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial d...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Nikles, Jane (Editor ), Mitchell, Geoffrey (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer, [2015]
Temas:
Drugs > Testing.
Crossover trials.
Double-Blind Method
Médicaments > Essais cliniques.
Études croisées.
MEDICAL > Pharmacology.
Crossover trials
Drugs > Testing
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Preface
  • Introduction
  • What are N-of-1 trials?- N-of-1 trials in the behavioural sciences
  • N-of-1 trials in medical contexts
  • Aggregated N-of-1 trials
  • Methodological considerations for N-of-1 trials
  • Randomization, allocation concealment and blinding
  • Data collection and quality control
  • Individual reporting of N-of-1 trials to patients and clinicians
  • Assessing and reporting adverse events
  • Research ethics and N-of-1 trials
  • Statistical analysis of N-of-1 trials
  • The economics of N-of-1 trials
  • Reporting N-of-1 trials to professional audiences
  • Single patient open trials
  • Systematic review and meta-analysis using N-of-1 trials
  • Where are N-of-1 trials headed?- Index.

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