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Potential risks and benefits of gain-of-function research : summary of a workshop /
On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respirato...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Autor Corporativo: | |
| Otros Autores: | , , , |
| Formato: | Electrónico Congresos, conferencias eBook |
| Idioma: | Inglés |
| Publicado: |
Washington, D.C. :
National Academies Press,
[2015]
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| Colección: | Online access: NCBI NCBI Bookshelf.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Sharples, Frances Ellen, |e rapporteur. | |
| 245 | 1 | 0 | |a Potential risks and benefits of gain-of-function research : |b summary of a workshop / |c Frances Sharples, Jo Husbands, Anne-Marie Mazza, Audrey Thevenon, and India Hook-Barnard, rapporteurs ; Board on Life Sciences, Division on Earth and Life Studies, Committee on Science, Technology, and Law, Policy and Global Affairs Division, Board on Health Sciences Policy, Institute of Medicine, National Research Council and Institute of Medicine of the National Academies. |
| 264 | 1 | |a Washington, D.C. : |b National Academies Press, |c [2015] | |
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| 500 | |a Title from PDF title page. | ||
| 504 | |a Includes bibliographical references. | ||
| 520 | 3 | |a On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting | |
| 536 | |a This study was supported by Contract No. 10002374 between the National Academy of Sciences and the National Institutes of Health, by the John D. and Catherine T. MacArthur Foundation, the Alfred P. Sloan Foundation, the Wellcome Trust, and by internal support from the National Academies. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the views of the organizations or agencies that provided support for the project. | ||
| 588 | 0 | |a Version viewed June 12, 2015. | |
| 505 | 0 | |a Introduction -- Assessing risks and benefits -- Gain-of-function research: background and alternatives -- Potential benefits of gain-of-function research -- Potential risks: biosafety and biosecurity -- Policy implications -- Key issues for risk/benefit assessment for gain-of-function research. | |
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| 650 | 0 | |a Epidemics |z United States |x Prevention |v Congresses. | |
| 650 | 0 | |a Risk assessment. | |
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| 650 | 2 | 2 | |a Coronavirus |x pathogenicity |
| 650 | 2 | 2 | |a Influenza A Virus, H1N1 Subtype |x pathogenicity |
| 650 | 2 | 2 | |a Risk Assessment |
| 651 | 2 | |a United States | |
| 650 | 6 | |a Évaluation du risque. | |
| 650 | 7 | |a risk assessment. |2 aat | |
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| 655 | 7 | |a Actes de congrès. |2 rvmgf | |
| 700 | 1 | |a Husbands, Jo L., |e rapporteur. | |
| 700 | 1 | |a Mazza, Anne-Marie, |e rapporteur. | |
| 700 | 1 | |a Thevenon, Audrey, |e rapporteur. | |
| 700 | 1 | |a Hook-Barnard, India, |e rapporteur. | |
| 710 | 2 | |a National Research Council (U.S.). |b Board on Life Sciences, |e issuing body. | |
| 710 | 2 | |a National Research Council (U.S.). |b Committee on Science, Technology, and Law, |e issuing body. | |
| 710 | 2 | |a Institute of Medicine (U.S.). |b Board on Health Sciences Policy, |e issuing body. | |
| 711 | 2 | |a Gain-of-Function Research (Symposium) |n (1st : |d 2014 : |c Washington, D.C.) | |
| 758 | |i has work: |a Potential risks and benefits of gain-of-function research (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGfVhVhRyDtH4MgMjYtyJP |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Sharples, Frances Ellen. |t Potential risks and benefits of gain-of-function research. |d Washington, D.C. : The National Academies Press, [2015] |z 9780309367837 |w (OCoLC)908339129 |
| 830 | 0 | |a Online access: NCBI NCBI Bookshelf. | |
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