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Phycotoxins : Chemistry and Biochemistry.
Dr Luis M Botana is Director of the Community Reference Laboratory for Marine Toxins and Head of the Department of Pharmacology, University of Santiago de Compostela, Spain. Dr Amparo Alfonso is Professor of Pharmacology, University of Santiago de Compostela, Spain.
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
Wiley,
2015.
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| Edición: | 2nd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Table of Contents; Title Page; Copyright; List of contributors; Preface; Chapter 1: Analysis of marine toxins: gaps on food safety control of marine toxins; Analysis of marine toxins and gaps on food safety control; Gaps on food safety control for marine toxins by chemical methods; Use of standards; New risks in the EU; References; Chapter 2: Pharmacology of ciguatoxins; Chemical structure of ciguatoxins; Voltage-gated sodium channels; Neurological symptoms of ciguatera; Physiological effects of ciguatoxin; Ciguatoxin neurotoxicity; Ciguatoxins, neurological perspectives; References.
- Chapter 3: Chemistry of pinnatoxinsIntroduction; Isolation; Bioactivity; Detection; Total chemical synthesis; Chemical stability; Conclusions; References; Chapter 4: Chemistry and analysis of PSP toxins; Introduction; Methods of analysis; Chemical methods; References; Chapter 5: Chemistry of palytoxin and its analogues; Introduction; Palytoxin; Palytoxin's analogues from Ostreopsis spp; Ostreocins from O. siamensis; References; Chapter 6: Pharmacology of palytoxins and ostreocins; Introduction; Origin and producing organisms; Toxin distribution and ecological aspects.
- Pharmacological target of PLTXsPalytoxin toxicology; Detection methods; Future perspectives; References; Chapter 7: Recent insights into anatoxin-a chemical synthesis, biomolecular targets, mechanisms of action and LC-MS detection; Anatoxin-a and analogues; Anatoxins' biomolecular targets and mechanisms of action; LC-MS detection; Conclusions and perspectives; Acknowledgements; References; Chapter 8: Therapeutics of marine toxins; Introduction; Marine toxins as a source of therapeutic compounds; Present marine toxins and derived compound uses.
- Future of marine toxins and derived compounds usesProblems and advancements in drug discovery from the seas; Conclusions; References; Chapter 9: Marine toxins as modulators of apoptosis; Introduction; Phycotoxins involved in apoptotic processes; Non-apoptotic cytotoxicity of phycotoxins; References; Chapter 10: Cyanobacterial toxins; Introduction; Chemistry of cyanotoxins; Distribution of cyanotoxins; Acknowledgments; References; Chapter 11: Marine toxins and climate change: the case of PSP from cyanobacteria in coastal lagoons; Introduction.
- Definition of coastal lagoons and main ecosystem characteristicsEcosystem goods and services and human exploitation of coastal lagoons; Eutrophication and climate change in coastal lagoons; Cyanobacteria in coastal lagoons; Paralytic shellfish poisoning and cyanobacteria in coastal lagoons; Conclusions; References; Chapter 12: Microalgae as a source of nutraceuticals; Introduction; Microalgal taxa; World biodiversity of microalgae; Microalgae in culture collections and under commercial cultivation; Commercial use of microalgae as nutraceuticals; Categories of nutraceuticals from microalgae.