Translational ADMET for drug therapy : principles, methods, and pharmaceutical applications /

Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, and decision-making tactics for pharmaceutical and preclinical scientists. Chapters cover case studies and in vivo, in vitro, and computational tools f...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Yanni, Souzan (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, New Jersey : John Wiley & Sons, Inc., [2015]
Temas:
Pharmacokinetics.
Drugs > Metabolism > Pharmacokinetics.
Drugs > Testing.
Drug development.
Chemotherapy.
Drugs > Side effects.
Drug Evaluation, Preclinical
Pharmacokinetics
Drug-Related Side Effects and Adverse Reactions
Pharmaceutical Preparations > metabolism
Drug Therapy
Pharmacocinétique.
Médicaments > Métabolisme > Pharmacocinétique.
Médicaments > Essais cliniques.
Médicaments > Développement.
Chimiothérapie.
Médicaments > Effets secondaires.
MEDICAL > Pharmacology.
Drugs > Side effects
Drugs > Testing
Drug development
Chemotherapy
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Translational Concept and Determination of Drug Absorption
  • Distribution: Principle, Methods, and Applications
  • Metabolism: Principle, Methods, and Applications
  • Excretion: Principle, Methods, and Applications for Better Therapy
  • Drug-Drug Interaction: From Bench to Drug Label
  • General Toxicology: Principle, Methods, and Applications
  • Toxicokinetics and Toxicity Testing in Drug Development
  • PBPK Modeling and In Silico Prediction for ADME and Drug-Drug Interaction
  • Translational Tools toward Better Drug Therapy in Human Populations
  • Phase 1-Phase 3 Clinical Studies, Procedures, Responsibilities, and Documentation
  • Regulatory Submission: MIST and Drug Safety Assessment.

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