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Corynebacterium glutamicum : from systems biology to biotechnological applications /
Corynebacterium glutamicum is most widely known for its role in the industrial production of L-glutamate and L-lysine and as a platform organism for the production of a variety of fine chemicals, biofuels and polymers. The organism's accessibility to genetic manipulation has resulted in a wealt...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Norfolk, UK :
Caister Academic Press,
[2015]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Burkovski, Anas, |e editor. | |
| 245 | 1 | 0 | |a Corynebacterium glutamicum : |b from systems biology to biotechnological applications / |c Anas Burkovski. |
| 264 | 1 | |a Norfolk, UK : |b Caister Academic Press, |c [2015] | |
| 264 | 4 | |c ©2015 | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed March 3, 2015). | |
| 505 | 0 | |6 880-01 |a Contributors; Current Books of Interest; Preface; 1: Trends in Corynebacterium glutamicum Research and Application; From glutamate producer to a biotechnology workhorse; Systems biology; Corynebacterium glutamicum as a synthetic biology platform; Corynebacterium glutamicum-based green technology; 2: Proteomics of Corynebacterium glutamicum; Introduction; Understanding Corynebacterium glutamicum physiology with proteomics: application examples; Methods of Corynebacterium glutamicum proteomics; Conclusion and outlook. | |
| 505 | 8 | |a 3: Developing Interpretation of Intracellular Metabolism of Corynebacterium glutamicum by Using Flux Analysis TechnologyIntroduction; Understanding the physiology of Corynebacterium glutamicum lysine production and glutamate production through conventional metabolic flux analysis; Fractional 13C enrichment-based metabolic flux analysis; Improvement in metabolic flux analysis precision; Conclusion; 4: Growth and Production Capabilities of Corynebacterium glutamicum: Interrogating a Genome-scale Metabolic Network Model; Introduction; The metabolic network of Corynebacterium glutamicum. | |
| 505 | 8 | |a Stoichiometric modelling fundamentalsModel validation; Predicting production capabilities for amino acids; Uncertainties in metabolic network models; Metabolic flux analysis; Conclusions; 5: Metabolic Engineering of Corynebacterium glutamicum for Alternative Carbon Source Utilization; Introduction; Engineering of Corynebacterium glutamicum for alternative carbon sources; Complex carbon sources; Summary and outlook; 6: Manipulation of Nitrogen Metabolism and Alternative Nitrogen Sources for Corynebacterium glutamicum; Ammonium assimilation in Corynebacterium glutamicum. | |
| 520 | |a Corynebacterium glutamicum is most widely known for its role in the industrial production of L-glutamate and L-lysine and as a platform organism for the production of a variety of fine chemicals, biofuels and polymers. The organism's accessibility to genetic manipulation has resulted in a wealth of data on its metabolism and regulatory networks; this in turn makes C. glutamicum the model organism of choice in white biotechnology. A key development in recent years has been the engineering of C. glutamicum to utilize a broader spectrum of carbon sources (e.g. glycerol, galactose and pentose suga. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Corynebacterium glutamicum. | |
| 650 | 2 | |a Corynebacterium glutamicum | |
| 650 | 4 | |a Biotechnology. | |
| 650 | 4 | |a Corynebacterium glutamicum. | |
| 650 | 4 | |a Science. | |
| 650 | 6 | |a Corynebacterium glutamicum. | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biology. |2 bisacsh | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Microbiology. |2 bisacsh | |
| 650 | 7 | |a Corynebacterium glutamicum |2 fast | |
| 776 | 0 | 8 | |i Print version: |a Burkovski, Andreas. |t Corynebacterium glutamicum : From Systems Biology to Biotechnological Applications. |d Portland : Caister Academic Press, ©2015 |z 9781910190050 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5897779 |z Texto completo |
| 880 | 8 | |6 505-00/(S |a Regulation of nitrogen metabolismManipulation of nitrogen metabolism for amino acid production; Overexpression, deletion and heterologous expression of glutamate dehydrogenase; Overexpression of glutamine synthetases; Influence of glutamate synthase on L-glutamate biosynthesis; Changing ammonium assimilation and amino acid production by manipulation of α-ketoglutarate supply; Influence of ammonium and glutamate transport systems on amino acid production; Manipulation of nitrogen regulation: influences on metabolite pools; Assimilation of alternative nitrogen sources; Concluding remarks. | |
| 880 | 8 | |6 505-01/(S |a 7: Transport, Degradation and Assimilation of Aromatic Compounds and their Regulation in Corynebacterium glutamicum Introduction; What do the Corynebacterium glutamicum genomes predict for degradation and assimilation of aromatic compounds?; Corynebacterium glutamicum grows on various aromatic compounds; Physiological adaptation of Corynebacterium glutamicum growing on aromatic compounds compared with carbohydrates; Uptake and transport of aromatic compounds in Corynebacterium glutamicum; Aromatic compounds degraded via protocatechuate branch of the β-ketoadipate pathway. | |
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