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Nanotechnology applications for tissue engineering /

Tissue engineering involves seeding of cells on bio-mimicked scaffolds providing adhesive surfaces. Researchers though face a range of problems in generating tissue which can be circumvented by employing nanotechnology. It provides substrates for cell adhesion and proliferation and agents for cell g...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Thomas, Sabu (Editor ), Grohens, Yves (Editor ), Ninan, Neethu (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier, [2015]
Colección:Micro & nano technologies.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Nanotechnology Applications for Tissue Engineering; Copyright Page; Contents; List of Contributors; About the Editors; Preface; 1 Nanomedicine and Tissue Engineering; 1.1 Introduction; 1.1.1 Nanomedicine; 1.1.2 Tissue Engineering; 1.2 Relationship of Nanomedicine and Tissue Engineering; 1.2.1 Nanomedicine Approaches in Bone Tissue Engineering; 1.2.2 Nanomedicine Approaches in Cardiac Tissue Engineering; 1.2.3 Nanomedicine Approaches in Skin Tissue Engineering; 1.2.4 Nanomedicine Approaches in Brain Tissue Engineering
  • 1.2.5 Nanomedicine Approaches for Other Tissue Engineering Disciplines1.3 Nanodrug Delivery Systems for Tissue Regeneration; 1.3.1 Nanotheranostics; 1.3.2 Nanoregeneration Medicine; 1.3.3 Nanodrug Delivery; 1.3.3.1 Dendrimers; 1.3.3.2 Liposomes; 1.3.3.3 Carbon Nanotubes; 1.3.3.4 Nanocomposite Hydrogel; 1.4 Medical Applications of Molecular Nanotechnology; 1.4.1 Nanorobots; 1.4.2 Cell Repair Machines; 1.5 Summary and Future Directions; References; 2 Biomaterials: Design, Development and Biomedical Applications; 2.1 Overview; 2.2 Design of Biomaterials; 2.2.1 Polymers; 2.2.2 Metals
  • 2.2.3 Composite Materials2.2.4 Ceramics; 2.3 Basic Considerations to Design Biomaterial; 2.4 Characteristics of Biomaterials; 2.4.1 Nontoxicity; 2.4.2 Biocompatible; 2.4.3 Absence of Foreign Body Reaction; 2.4.4 Mechanical Properties and Performance; 2.5 Fundamental Aspects of Tissue Responses to Biomaterials; 2.5.1 Injury; 2.5.2 Blood-Material Interactions and Initiation of the Inflammatory Response; 2.5.3 Provisional Matrix Formation; 2.5.4 Acute Inflammation; 2.5.5 Chronic Inflammation; 2.5.6 Granulation Tissue; 2.5.7 Foreign Body Reaction; 2.5.8 Fibrosis and Fibrous Encapsulation
  • 2.6 Evaluation of Biomaterial Behavior2.6.1 Assessment of Physical Properties; 2.6.2 In vitro Assessment; 2.6.3 In vivo Assessment; 2.7 Properties of Biomaterials Assessed Through In Vivo Experiments; 2.7.1 Sensitization, Irritation, and Intracutaneous Reactivity; 2.7.2 Systemic, Subacute, and Subchronic Toxicity; 2.7.3 Genotoxicity; 2.7.4 Implantation; 2.7.5 Hemocompatibility; 2.7.6 Chronic Toxicity; 2.7.7 Carcinogenicity; 2.7.8 Reproductive and Developmental Toxicity; 2.7.9 Biodegradation; 2.7.10 Immune Responses; 2.8 Applications of Biomaterials; 2.8.1 Orthopedic Applications
  • 2.8.2 Ophthalmologic Applications2.8.3 Cardiovascular Applications; 2.8.4 Dental Applications; 2.8.5 Wound Dressing Applications; 2.8.6 Other Applications; 2.9 Future Directions in Biomaterials; 2.10 Conclusions; Acknowledgments; References; 3 Electrospinning of Polymers for Tissue Engineering; 3.1 Introduction; 3.2 History of Electrospinning; 3.3 Experimental Setup and Basic Principle; 3.3.1 Theoretical Background; 3.4 Effects of Parameters on Electrospinning; 3.4.1 Solution Parameters; 3.4.2 Concentration and Viscosity; 3.4.3 Molecular Weight; 3.4.4 Surface Tension