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Hyaluronic acid : preparation, properties, application in biology and medicine /
Hyaluronic acid is an essential part of connective, epithelialand neural tissues, and contributes to cell proliferation andmigration. It is used as a stimulating agent for collagen synthesisand is a common ingredient in skin-care products, a multi-billiondollar industry, as it is believed to be a ke...
| Clasificación: | Libro Electrónico |
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| Autores principales: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
John Wiley & Sons,
2015.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Title Page; Copyright Page; Contents; Foreword; Introduction; Chapter 1 The History of Hyaluronic Acid Discovery, Foundational Research and Initial Use; 1.1 Discovery; 1.2 Foundational Research; 1.3 Initial Medical Applications; 1.4 Sources of Hyaluronan; 1.5 Current Medical Study and Use; 1.6 Impact and Future Directions; References; Chapter 2 The Biological Role of Hyaluronic Acid; 2.1 Hyaluronic Acid Phylogenesis; 2.1.1 Polysaccharide Structure and the Problems of Phylogenesis; 2.1.2 Physico-Chemical and Functional Differences of Polysaccharides
- 2.1.3 Biochemical Features of Hyaluronic Acid and Other Glycosaminoglycans2.2 Functions of Hyaluronan in Human Ontogenesis; 2.2.1 Role of Hyaluronic Acid in Fertilization; 2.2.2 Hyaluronan and Other Glucosaminoglycans in Cell Division, Migration and Differentiation; 2.2.3 Hyaluronic Acid and Sulfated Glycosaminoglycans in Maintaining a Differentiated Status of Cells; 2.2.4 Hyaluronan and Induction of Cellular Cycles for Differentiated Cells; 2.2.5 The Source of Hyaluronic Acid's Functional Properties and the Dynamics of its Synthesis and Degradation
- 2.2.6 The Rules of Biopolymer Functional Cleavage2.3 Hyaluronan Signalling Systems; 2.4 Hyaluronan Functions in the Extracellular Matrix; 2.4.1 Extracellular Space; 2.4.2 Composition and Functioning of the Extracellular Matrix; 2.4.3 The Role of Hyaluronan in Transportation of Substances through the Extracellular Matrix: Diffusion, Osmosis, Electro-Osmosis and Vesicular Transportation; 2.4.4 Hyaluronan in the Extracellular Matrix of Different Connective Tissues; References; Chapter 3 Methods of Hyaluronic Acid Production; 3.1 Hyaluronan Sources and Extraction
- 3.1.1 Hyaluronan Production from Animal Sources: General Methods3.1.2 Hyaluronan Purification; 3.1.3 The Chemical Production of Hyaluronan from Chicken Combs; 3.1.4 HA Production for Ophthalmology; 3.2 Bacterial Methods of Hyaluronic Acid Production; 3.3 Hyaluronan Destruction during Production, Storage and Sterilization; 3.4 Enzymatic Destruction of Hyaluronan; 3.4.1 Hyaluronidase Classification; 3.4.2 Properties and Functions of Hyaluronidases; 3.5 Non-Enzymatic Destruction of Hyaluronan; 3.5.1 Acid-Base Hydrolysis of Hyaluronan; 3.5.2 Oxidation-Reduction Depolymerization of Hyaluronan
- 3.6 Quality of Hyaluronan Commercial Products of Animal and Bacterial OriginReferences; Chapter 4 Molecular and Supramolecular Structure of Hyaluronic Acid; 4.1 Primary Structure of Hyaluronic Acid; 4.2 Structure of Hyaluronan in Solution; 4.3 Rheological Properties of Hyaluronic Acid; References; Chapter 5 Chemical Modifications, Solid Phase, Radio-Chemical and Enzymatic Transformations of Hyaluronic Acid; 5.1 Main Characteristics of Cross-Linked Hydrogels; 5.2 Methods of Hyaluronic Acid Cross-Linking; 5.2.1 Cross-Linking with Carbodiimides; 5.2.2 Cross-Linking with Aldehydes