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Bioinspired and biomimetic polymer systems for drug and gene delivery /
Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid syst...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Weinheim [Germany] :
Wiley-VCH,
[2015]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Related Titles; Title Page; Copyright; Foreword; List of Contributors; Preface; Chapter 1: Backbone Degradable and Coiled-Coil Based Macromolecular Therapeutics; 1.1 Introduction; 1.2 Water-Soluble Polymers as Carriers of Anticancer Drugs; 1.3 Drug-Free Macromolecular Therapeutics
- A New Paradigm in Drug Delivery; 1.4 General Summary and Outlook; Acknowledgments; References; Chapter 2: Dendritic Polymers as Targeting Nanoscale Drug Delivery Systems for Cancer Therapy; 2.1 Introduction; 2.2 Functional Dendritic Polymers Based Drug Delivery Vehicles for Targeting Tumor Therapy via EPR Effect.
- 2.3 Tumor Targeting Moieties Functionalized Dendritic Drug Delivery Vehicles for Cancer Therapy2.4 Conclusion; References; Chapter 3: Composite Colloidal Nanosystems for Targeted Delivery and Sensing; 3.1 Introduction; 3.2 Objective; 3.3 Cellular Behavior of the Carrier; 3.4 Applications; 3.5 Conclusions; Abbreviations; References; Chapter 4: Polymeric Micelles for Cancer-Targeted Drug Delivery; 4.1 Introduction; 4.2 Micelle Formulations in Clinical Development; 4.3 Particle Size of Micelles; 4.4 Morphology of Micelles.
- 4.5 Targeting Design of Micelles for Enhanced Accumulation and Cell Internalization4.6 Functional Designs of Micelles; 4.7 Design of Micelles for Gene Delivery; 4.8 Challenge and Future Perspective; References; Chapter 5: Biomimetic Polymers for In Vivo Drug Delivery; 5.1 Introduction; 5.2 Commonly Used Biomimetic Polymers and Their Applications in DDS; 5.3 Challenges and Perspectives; References; Chapter 6: Drug Delivery from Protein-Based Nanoparticles; 6.1 Introduction; 6.2 Preparation of Protein-Based Nanoparticles; 6.3 Drug Delivery from Albumin-Based Nanoparticles.
- 6.4 Drug Delivery from Gelatin-Based Nanoparticles6.5 Drug Delivery from Other Protein-Based Nanoparticles; References; Chapter 7: Polymeric Gene Carriers; 7.1 Gene Therapy and Gene Carriers; 7.2 Polymeric Gene Carriers; 7.3 PEI Grafting Modification Polymeric Gene Carriers; 7.4 Low Molecular Weight (LWM) PEI Base Polymeric Gene Carriers; 7.5 Targeted Shielding System for Polymeric Gene Carriers; 7.6 Conclusion; References; Chapter 8: pH-Sensitive Polymeric Nanoparticles as Carriers for Cancer Therapy and Imaging; 8.1 Introduction; 8.2 pH-Sensitive Polymers.
- 8.3 pH-Sensitive Polymers as Drug Carriers8.4 pH-Sensitive Polymers for Bioimaging; 8.5 Conclusions; References; Chapter 9: Charge-Reversal Polymers for Biodelivery; 9.1 Applications of Cationic Polymers in Biodelivery; 9.2 Barriers for Cationic Polymers in In vitro and In vivo Applications; 9.3 Characteristic pH Gradients in Tumor Interstitium and Endo/Lysosomes; 9.4 Chemistry of Charge-Reversal Polymers Based on Acid-Labile Amides; 9.5 Applications of Charge-Reversal Polymers in Biodelivery Systems; 9.6 Perspectives; References.