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Metal-containing enzymes /
Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Elsevier/Academic Press,
2014.
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| Edición: | First edition. |
| Colección: | Advances in protein chemistry and structural biology ;
v. 97. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Metal-Containing Enzymes; Copyright; Contents; Contributors; Preface; Chapter 1: Type-3 Copper Proteins: Recent Advances on Polyphenol Oxidases; 1. Introduction; 2. Primary Structure and Molecular Weights of PPOs; 2.1. General sequence structure; 2.2. Core domain, C-terminal domain, and its proteolytic cleavage site; 2.3. Conserved amino acid motifs in the core domain; 2.4. Conserved amino acid motifs in the C-terminal domain; 2.5. Transit peptide and location of PPOs; 2.6. Sequence homologies within PPOs; 2.7. In vitro activation of PPOs; 2.8. In vivo activation of PPOs
- 2.9. Mutants of PPOs2.9.1. Mutants of plant PPOs; 2.9.2. Mutants of fungal PPOs; 2.9.3. Mutants of bacterial PPOs; 3. Oxo Complex; 3.1. Oxo complex investigated by UV/vis absorption spectroscopy; 3.2. Oxo complex investigated by CD spectroscopy; 3.3. Oxo complex investigated by resonance Raman spectroscopy; 3.4. Oxo complex of catechol oxidase; 3.5. Oxo complex of tyrosinase; 3.6. Oxo complex of aureusidin synthase; 3.7. Oxo complex of hemocyanin; 4. X-ray Crystallographic Structural Data of PPOs and Hemocyanins; 4.1. Published structures in the protein data bank
- 4.1.1. Published structures in the PDB of hemocyanins4.1.2. Published structures in the PDB of catechol oxidases; 4.1.3. Published structures in the PDB of tyrosinases; 4.2. Structural differences of tyrosinases and catechol oxidases; 5. Conclusions and Outlook; Acknowledgments; References; Chapter 2: Biophysical Studies of Matrix Metalloproteinase/Triple-Helix Complexes; 1. MMPs and Collagen Hydrolysis; 2. Structures of Full-Length, Collagenolytic MMPs in Solution and in the Solid State; 3. Structural Evaluation of MMP Interactions with Collagen; 4. Mechanism of Collagenolysis