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Leishmania : current biology and control /
In this timely book respected Leismania experts distil the important current research highlighting the most insightful discoveries in the field. Topics covered include: modulation of host miRNA; heat shock proteins; Iron in the Leishmania-macrophage interaction; oxidative and nitrosative stress resp...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Norfolk, England :
Caister Academic Press,
2015.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
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| 001 | EBOOKCENTRAL_ocn896842821 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
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| 016 | 7 | |a 016965346 |2 Uk | |
| 016 | 7 | |a 016966213 |2 Uk | |
| 020 | |a 9781908230539 |q (e-book) | ||
| 020 | |a 1908230533 |q (e-book) | ||
| 020 | |z 9781908230522 |q (print) | ||
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| 035 | |a (OCoLC)896842821 | ||
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| 082 | 0 | 4 | |a 593.18 |2 23 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Leishmania : |b current biology and control / |c edited by Subrata Adak and Rupak Datta ; contributors, Subrata Adak [and thirty-three others]. |
| 264 | 1 | |a Norfolk, England : |b Caister Academic Press, |c 2015. | |
| 264 | 4 | |c Ã2015 | |
| 300 | |a 1 online resource (258 pages) : |b illustrations, tables | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references at the end of each chapters and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (ebrary, viewed November 11, 2014). | |
| 520 | |a In this timely book respected Leismania experts distil the important current research highlighting the most insightful discoveries in the field. Topics covered include: modulation of host miRNA; heat shock proteins; Iron in the Leishmania-macrophage interaction; oxidative and nitrosative stress response; cell death; strategies for immune evasion; STAT signalling; parasite modulation of toll-like receptors in macrophages; T cells in Leishmania infection; vaccine biology; inhibitors of Leishmania DNA topoisomerases; and mechanism of drug resistance in visceral Leishmaniasis. An essential text fo. | ||
| 505 | 0 | |a Contributors; Current Books of Interest; Preface; 1: Modulation of Host Cell miRNA Expression During Leishmania Infection and Emergence of miRNA as a New Therapeutic Molecule; miRNA-mediated gene regulation in metazoan animals; miRNA as regulator of cholesterol metabolism in mammals; Cholesterol regulates pathogenesis of Leishmania donovani; Leishmania-mediated changes in cholesterol production in mammals; miRNA expression affected by parasite; Mechanism of miRNA alteration by Leishmania; Factors important for host cell miRNA alteration during infection; miRNA as therapeutic agent | |
| 505 | 8 | |a Future of miRNA as a therapeutic agent against visceral leishmaniasis2: Heat Shock Proteins of Leishmania: Chaperones in the Driver's Seat; Introduction: heat shock proteins; Heat shock proteins in Leishmania spp.; Leishmania and the cell stress; The pitfalls of analogy-based assumptions; The chaperone machinery and signal transduction in Leishmania; Open questions; Future trends; Acknowledgements; 3: Role of Iron in Leishmania-Macrophage Interaction; Introduction; Aqueous chemistry and toxicity of iron; Role of iron in physiology; Role of iron in the host-parasite interaction | |
| 505 | 8 | |a Special need of iron for LeishmaniaMammalian iron homeostasis components important for sequestering iron; Regulation of cellular iron metabolism of mammalian host; Source of host iron and its acquisition systems in Leishmania; Summary and future aspects; 4: Oxidative and Nitrosative Stress Response in Leishmania; Introduction; Sources of superoxide and hydrogen peroxide in Leishmania; Targets of reactive oxygen species in Leishmania; Defence against reactive oxygen species; Nitrosative stress in Leishmania; Generation of reactive nitrogen species | |
| 505 | 8 | |a Targets of reactive nitrogen species (RNS) in LeishmaniaCellular defences against nitrosative stress in Leishmania; Conclusion; Future perspectives; 5: Cell Death in a Kinetoplastid Parasite, the Leishmania spp.; Introduction; Life cycle of Leishmania spp.; Treatment of leishmaniasis; Programmed cell death (PCD); Programmed cell death in protozoan parasites; Relevance of studying cell death in Leishmania; Apoptosis in Leishmania; Natural cell death during cell cycle; Induction of cell death by anti-leishmanial drugs; Oxidative stress induced cell death | |
| 505 | 8 | |a Role of apoptotic mimicry and apoptosis in LeishmaniaAutophagy in Leishmania; Future trends; Conclusion; 6: Elucidating the Strategies of Immune Evasion by Leishmania; Introduction; Defying recognition by the host: modulation of Toll-like receptor-mediated signalling; Deactivation of host signalling: mitogen-activated protein (MAP) kinases and phosphatases; Disarming the enemy: inhibition of host microbicidal molecules; Delaying phagosome maturation: buying time for promastigote to amastigote conversion; Creating a favourable environment: polarization of Th (T-helper cell) response | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Leishmania. | |
| 650 | 1 | 2 | |a Leishmaniasis |x prevention & control |
| 650 | 2 | |a Leishmania | |
| 650 | 6 | |a Leishmania. | |
| 650 | 7 | |a Leishmania |2 fast | |
| 700 | 1 | |a Adak, Subrata, |e editor, |e contributor. | |
| 700 | 1 | |a Datta, Rupak, |e editor. | |
| 758 | |i has work: |a Leishmania (Adak) (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGHXtwtfbdWHBjvWBGVxcK |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |t Leishmania. |d Norfolk, England : Caister Academic Press, [2015] |z 9781908230522 |w (OCoLC)880861769 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5897804 |z Texto completo |
| 936 | |a BATCHLOAD | ||
| 938 | |a Askews and Holts Library Services |b ASKH |n AH27216017 | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL5897804 | ||
| 938 | |a ebrary |b EBRY |n ebr10958799 | ||
| 938 | |a YBP Library Services |b YANK |n 11849889 | ||
| 994 | |a 92 |b IZTAP | ||