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Review of the formaldehyde assessment in the national toxicology program 12th report on carcinogens /

"Many people in the United States are exposed to formaldehyde. Exposure can occur from environmental sources (for example, combustion processes, building materials, and tobacco smoke) or in occupational settings (for example, the furniture, textile, and construction industries). Formaldehyde ex...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: National Research Council (U.S.). Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press, [2014]
Colección:Online access: NCBI NCBI Bookshelf.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Review of the formaldehyde assessment in the national toxicology program 12th report on carcinogens /  |c Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies. 
264 1 |a Washington, D.C. :  |b National Academies Press,  |c [2014] 
264 4 |c ©2014 
300 |a 1 online resource (xiii, 232 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references. 
505 0 |a Review of the Formaldehyde Profile in the National Toxicology Program 12th Report on Carcinogens -- Independent Assessment of Formaldehyde -- Appendix A: Biographic Information on the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens -- Appendix B: Statement of Task of the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens -- Appendix C: Exposure Assessment in Epidemiologic Carcinogenicity Studies -- Appendix D: Literature-Search Strategies Completed in Support of the Committee's Independent Assessment of Formaldehyde -- Appendix E: Genotoxicity and Mutagenicity Summary Tables. 
520 |a "Many people in the United States are exposed to formaldehyde. Exposure can occur from environmental sources (for example, combustion processes, building materials, and tobacco smoke) or in occupational settings (for example, the furniture, textile, and construction industries). Formaldehyde exposure also has endogenous sources--it is produced intracellularly as a component of the one carbon pool intermediary metabolism pathway. Scientists have studied formaldehyde for decades to determine whether exogenous formaldehyde exposure may be associated with cancer in humans. In 1981, The National Toxicology Program (NTP) first listed formaldehyde in the 2nd Report on Carcinogens as "reasonably anticipated to be a human carcinogen". In 2011, NTP upgraded the listing of formaldehyde to "known to be a human carcinogen". Following the new listing, Congress directed the Department of Health and Human Services to arrange for the National Academy of Sciences to independently review formaldehyde's substance profile and listing. This report presents the findings and conclusions of the committee formed in response to the congressional request. Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens concurs with NTP that there is sufficient evidence in studies that had adequate characterization of relevant exposure metrics to enable a strong conclusion about the association between formaldehyde exposure and cancer in humans. Additionally, the authoring committee independently reviewed the scientific evidence from studies in humans, experimental animals, and other studies relevant to the mechanisms of carcinogenesis and made level-of-evidence conclusions. This report finds clear and convincing epidemiologic evidence of an association between formaldehyde exposure and nasopharyngeal and sinonasal cancers in humans."--Publisher's description 
588 0 |a Print version record. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
610 2 2 |a National Toxicology Program (U.S.) 
650 0 |a Formaldehyde  |x Environmental aspects. 
650 0 |a Formaldehyde  |x Toxicology. 
650 0 |a Environmental toxicology. 
650 0 |a Formaldehyde  |x Risk assessment. 
650 0 |a Risk assessment. 
650 1 2 |a Environmental Pollutants  |x toxicity 
650 1 2 |a Formaldehyde  |x toxicity 
650 2 2 |a Carcinogens  |x toxicity 
650 2 2 |a Risk Assessment 
650 2 2 |a Program Evaluation 
651 2 |a United States 
650 2 |a Ecotoxicology 
650 6 |a Formaldéhyde  |x Aspect de l'environnement. 
650 6 |a Formaldéhyde  |x Toxicologie. 
650 6 |a Écotoxicologie. 
650 6 |a Formaldéhyde  |x Évaluation du risque. 
650 6 |a Évaluation du risque. 
650 7 |a risk assessment.  |2 aat 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Risk assessment  |2 fast 
650 7 |a Environmental toxicology  |2 fast 
650 7 |a Formaldehyde  |x Environmental aspects  |2 fast 
650 7 |a Formaldehyde  |x Toxicology  |2 fast 
655 2 |a Review 
710 2 |a National Research Council (U.S.).  |b Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens. 
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