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Human longevity : omega-3 fatty acids, bioenergetics, molecular biology, and evolution /

More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age a...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Valentine, R. C. (Raymond Carlyle), 1936- (Autor), Valentine, David L. (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Boca Raton : CRC Press, 2014.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Valentine, R. C.  |q (Raymond Carlyle),  |d 1936-  |e author.  |1 https://id.oclc.org/worldcat/entity/E39PCjwvyjbryvqkV4MR3rPgBq 
245 1 0 |a Human longevity :  |b omega-3 fatty acids, bioenergetics, molecular biology, and evolution /  |c Raymond C. Valentine and David L. Valentine. 
264 1 |a Boca Raton :  |b CRC Press,  |c 2014. 
300 |a 1 online resource 
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504 |a Includes bibliographical references and index. 
588 0 |a CIP data; item not viewed. 
505 0 |a Front Cover; Contents; Preface; Acknowledgments; About the Authors; Chapter 1: Mitochondrial Hypothesis of Aging Is Undergoing Revision; Chapter 2: Oxidative Stress Defined as a Deadly Free Radical-Mediated Chain Reaction : Case History of Paraquat; Chapter 3: Membranes of Deep-Sea Bacteria as Surrogates for Mitochondrial Membranes of Humans; Chapter 4: Protective Mechanisms for EPA Membranes in C. elegans and Their Relationship to Life Span. 
505 8 |a Chapter 5: Remarkable Longevity of Queens of Social Insects Likely Involves Dietary Manipulation to Minimize Levels of Polyunsaturates and Decrease Membrane PeroxidationChapter 6: Membrane Peroxidation Hypothesis Helps Explain Longevity in Birds, Rodents, and Whales; Chapter 7: Did Longevity Help Humans Become Super Humans?; Chapter 8: Mitochondrial Diseases and Aging Have Much in Common; Chapter 9: Revised Mitochondrial Hypothesis of Aging Highlights Energy Deficiency Caused by Errors of Replication (Mutations) of mtDNA; Chapter 10: Benefits of Polyunsaturated Mitochondrial Membranes. 
505 8 |a Chapter 11: Mitochondrial Membranes as a Source of Reactive Oxygen Species (ROS)Chapter 12: Mitochondrial Membranes as Major Targets of Oxidation; Chapter 13: Apoptosis Caused by Oxidatively Truncated Phospholipids Can Be Reversed by Several Mechanisms, Especially Enzymatic Detoxification; Chapter 14: Selective Targeting of HUFAs Away from Cardiolipin and Beta-Oxidation Combine to Protect Mitochondrial Membranes against Oxidative Damage; Chapter 15: Oxygen Limitation Protects Mitochondrial Phospholipids, Especially Cardiolipin. 
505 8 |a Chapter 16: Uncoupling Proteins (UCPs) of Mitochondria Purposely Waste Energy to Prevent Membrane DamageChapter 17: Mitochondrial Fission Protects against Oxidative Stress by Minting a Continuous Supply of Cardiolipin and Other Polyunsaturated Phospholipids; Chapter 18: Mitophagy Eliminates Toxic Mitochondria; Chapter 19: Longevity Genes Likely Protect Membranes; Chapter 20: Aging as a Cardiolipin Disease That Can Be Treated; Back Cover. 
520 |a More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman's famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membran. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Aging  |x Genetic aspects. 
650 0 |a Mitochondria. 
650 0 |a Oxidative stress. 
650 0 |a Omega-3 fatty acids  |x Health aspects. 
650 0 |a Docosahexaenoic acid. 
650 2 |a Cellular Senescence  |x physiology 
650 2 |a Docosahexaenoic Acids 
650 2 |a Mitochondria 
650 2 |a Oxidative Stress 
650 6 |a Vieillissement  |x Aspect génétique. 
650 6 |a Mitochondries. 
650 6 |a Stress oxydatif. 
650 6 |a Acide docosahexaénoïque. 
650 7 |a Docosahexaenoic acid  |2 fast 
650 7 |a Aging  |x Genetic aspects  |2 fast 
650 7 |a Mitochondria  |2 fast 
650 7 |a Omega-3 fatty acids  |x Health aspects  |2 fast 
650 7 |a Oxidative stress  |2 fast 
700 1 |a Valentine, David L.,  |e author. 
776 0 8 |i Print version  |z 9781466594869 
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