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Atherosclerosis : risks, mechanisms, therapies /
Comprehensive and in-depth in its coverage, Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy reviews the recent progress in atherosclerosis research and offers cutting edge perspectives from experts in the field. Written by an international team of authors including...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, New Jersey :
Wiley Blackwell,
[2014]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Title Page; Copyright Page; Contents; Contributors; Foreword; Preface; Section I Risk Factors: Old and New; Chapter 1 Lipoproteins; Brief History of Cholesterol and Atherosclerosis; Lipoproteins; LDL and Atherosclerosis; Triglyceride-Rich Lipoproteins and Atherosclerosis; HDL and Atherosclerosis; Summary; References; Chapter 2 Role of Dysglycemia in Atherosclerosis; Introduction; Molecular Mechanisms by Which Dysglycemia Accelerates Atherosclerosis; Dysglycemia and Endothelial Cells; Dysglycemia and Vascular Smooth Muscle Cells; Dysglycemia and Macrophages; Conclusion; Acknowledgments.
- Mechanisms of Flow-Induced InflammationConclusions; References; Chapter 5 Homocysteine: A Controversial Cardiovascular Risk Factor; Introduction; Epidemiological Studies: Establishment of Homocysteine as a Risk Factor; Animal Models of Hyperhomocysteinemia; Clinical Intervention Trials; Summary and Perspectives; References; Chapter 6 Hypertension as a Risk Factor for Atherosclerosis; Introduction; Evidence Linking Atherosclerosis and Hypertension; Molecular and Cellular Mechanisms Linking Hypertension and Atherosclerosis; Implications for Treatment and Future Directions; References.
- Chapter 7 The Genetics of Atherosclerosis: From Polymorphisms to PopulationsIntroduction; Lessons from Mendelian Diseases-Familial Hypercholesterolemia; Role for Genetic Diagnosis and Screening; Genetically Isolated Population Studies: Implications for Atherosclerosis in the General Population; GWAS to Identify Atherosclerosis Risk Genes in the General Population; Identification of a Risk Allele Located at 9P21 by GWAS; Technologic Advances and the Future; Conclusion; Acknowledgments; References; Chapter 8 Life Style; Introduction; Lifestyle Factors and Cardiovascular Disease.
- Lifestyle Factors and Cardiovascular Disease in the YoungPhysical Activity; Diet and Nutrition; Environmental Effects; Ambient Air Pollution; Other Environmental Factors; Summary; References; Section II Cellular Mechanisms; Chapter 9 Endothelial Cells; Introduction; Endothelial Nitric Oxide; Flow and Arterial Shear Stress; Peroxisome Proliferator-Activated Receptor Nuclear Receptor Family; Endothelial Progenitor Cells; Future Directions; References; Chapter 10 Vascular Smooth Muscle Cells; Introduction; SMCS in Atheroma Progression; Extrinsic Control of SMC Biology.