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Structure-based design of drugs and other bioactive molecules : tools and strategies /
In contrast to previous texts focusing on either computational, structural or synthetic methods, this one-of-a-kind guide integrates all three skill sets for a complete picture of contemporary structure-based design. As a result, this practical book demonstrates how to develop a high-affinity ligand...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
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| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Weinheim :
Wiley-VCH,
2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | In contrast to previous texts focusing on either computational, structural or synthetic methods, this one-of-a-kind guide integrates all three skill sets for a complete picture of contemporary structure-based design. As a result, this practical book demonstrates how to develop a high-affinity ligand with drug-like properties for any given drug target for which a high-resolution structure exists. The authors, both of whom have successfully designed drug-like molecules that were later developed into marketed drugs, use numerous examples of recently developed drugs to present best practice in. |
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| Descripción Física: | 1 online resource (476 pages) |
| Bibliografía: | Includes bibliographical references at the end of each chapters and index. |
| ISBN: | 9783527665211 3527665218 9783527665242 3527665242 3527665234 9783527665235 |