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Proteomics : targeted technology, innovations and applications /
Targeted proteomics is a technology for detecting proteins of interest with high sensitivity, quantitative accuracy, and reproducibility. The analysis of a pre-defined group of proteins provides precise, quantitative, and sensitive data to scientists and clinicians and can provide information on a s...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Norfolk, England :
Caister Academic Press,
2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Proteomics : |b targeted technology, innovations and applications / |c edited by Manuel Fuentes and Joshua LaBaer. |
| 264 | 1 | |a Norfolk, England : |b Caister Academic Press, |c 2014. | |
| 264 | 4 | |c ©2014 | |
| 300 | |a 1 online resource (197 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references at the end of each chapters and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (ebrary, viewed July 17, 2014). | |
| 505 | 0 | |a Contributors; Current books of interest; Preface; 1: Serum Proteomics for Studying Disease Pathogenesis and Identification of Disease Biomarkers; Introduction; Challenges of serum proteome analysis; Proteomic techniques in serum profiling; Applications; Conclusion; 2: Serum Profiling by Targeted Proteomics for Biomarker Discovery; Biomarker discovery; Targeted proteomics; Serum profiling by targeted proteomics; Conclusions; 3: Targeted Proteomics: Applications in the Study of Liver Disorders; The liver; Shotgun proteomics and liver disorders. | |
| 505 | 8 | |a MS-based targeted proteomics: selected reaction monitoring for protein detection and quantitationProtein regulation: targeted analysis of post-translational modifications based on enrichment procedures; Concluding remarks and future perspectives; 4: Targeted Proteomics for Chronic Lymphocytic Leukaemia; Introduction; Epidemiology and incidence; Clinical presentation; Monoclonal B lymphocytosis (MBL); Genetic and epigenetic analysis of CLL; Proteomics profiles in B-cell malignancies; Proteome analysis of B-cell maturation; Quantitative proteomics. | |
| 505 | 8 | |a 'Shot gun' proteomic studies on B-cell malignanciesConclusions and future directions; 5: Protein Microarrays: A Versatile Tool for Scientific Discovery; Introduction; Basic research applications; Clinical research applications; Data analysis and bioinformatics; Outlook and perspective; 6: Bioinformatics Challenges in Targeted Proteomics; Introduction; Experimental design; Data acquisition and data processing; Noise reduction and normalization; Data interpretation. | |
| 505 | 8 | |a 7: Standardized Formats, Report Information Guidelines, Mass Spectrometry-based Repositories and Application Programming Interfaces for Implementing Data Standards in ProteomicsBackground: HUPO-PSI; Standardization pillars: MIAPE guidelines, XML-based standard formats and controlled vocabularies; Proteomics repositories and databases; Application Programming Interfaces (APIs) for the integration of data standards into laboratory pipelines; Bioinformatics tools for creating and managing proteomics data standards; Data analysis and reporting tools; Conclusions. | |
| 505 | 8 | |a 8: Clinical Protein Science and Targeted Mass Spectrometric Assays -- New Frontiers in Disease Link and BiobankingThe unmet needs and progresses in modern healthcare; Building new medical frontiers in modern society; Impact to society of personalized medicines; Biobanking; Protein biomarkers and targeted analysis; Prostate cancer protein biomarker analysis; Conclusions; Index. | |
| 520 | |a Targeted proteomics is a technology for detecting proteins of interest with high sensitivity, quantitative accuracy, and reproducibility. The analysis of a pre-defined group of proteins provides precise, quantitative, and sensitive data to scientists and clinicians and can provide information on a subset of proteins important for their biological function. In this volume, a panel of high-profile contributors provides an overview of targeted proteomics in biomedical science. The book is focused on current state-of-the-art technology and applications, and it will be a valuable source of informat. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Proteomics. | |
| 650 | 0 | |a Proteins |x Structure. | |
| 650 | 0 | |a Protein binding. | |
| 650 | 0 | |a Gene expression. | |
| 650 | 0 | |a Post-translational modification. | |
| 650 | 2 | |a Proteomics | |
| 650 | 2 | |a Protein Binding | |
| 650 | 2 | |a Gene Expression | |
| 650 | 6 | |a Protéomique. | |
| 650 | 6 | |a Protéines |x Structure. | |
| 650 | 6 | |a Protéines |x Fixation. | |
| 650 | 6 | |a Expression génique. | |
| 650 | 6 | |a Protéines |x Modification post-traductionnelle. | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biochemistry. |2 bisacsh | |
| 650 | 7 | |a Gene expression |2 fast | |
| 650 | 7 | |a Post-translational modification |2 fast | |
| 650 | 7 | |a Protein binding |2 fast | |
| 650 | 7 | |a Proteins |x Structure |2 fast | |
| 650 | 7 | |a Proteomics |2 fast | |
| 700 | 1 | |a Fuentes, Manuel, |e editor. | |
| 700 | 1 | |a LaBaer, Joshua, |e editor. | |
| 758 | |i has work: |a Proteomics (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGTCrB6yCG3gv687XG8VFq |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |t Proteomics : targeted technology, innovations and applications. |d Norfolk, England : Caister Academic Press, ©2014 |h vii, 185 pages |z 9781908230461 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5897822 |z Texto completo |
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