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An introduction to high content screening : imaging technology, assay development, and data analysis in biology and drug discovery /

Using a collaborative and interdisciplinary author base withexperience in the pharmaceutical industry and academia, this book is a practical resource for high content (HC) techniques. Instructs readers on the fundamentals of highcontent screening (HCS) techniques ; Focuses on practical and widely-us...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Haney, Steven A. (Editor ), Bowman, Doug, active 2014 (Editor ), Chakravarty, Arijit (Editor ), Davies, Anthony, active 2014 (Editor ), Shamu, Caroline (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, New Jersey : John Wiley & Sons Inc., [2015]
Temas:
Acceso en línea:Texto completo

MARC

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245 0 3 |a An introduction to high content screening :  |b imaging technology, assay development, and data analysis in biology and drug discovery /  |c editors, Steven A. Haney and Doug Bowman ; associate editors, Arijit Chakravarty, Anthony Davies, and Caroline Shamu. 
264 1 |a Hoboken, New Jersey :  |b John Wiley & Sons Inc.,  |c [2015] 
300 |a 1 online resource 
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504 |a Includes bibliographical references and index. 
505 0 |a Introduction / Steven Haney -- Fluorescence and cell labeling / Anthony Davies, Steven Haney -- Microscopy fundamentals / Steven Haney, Anthony Davies, Doug Bowman -- Image processing / John Bradley, Doug Bowman, Arijit Chakravarty -- Selecting and setting up a high content imaging platform / Craig Furman, Doug Bowman, Anthony Davies, Caroline Shamu, Steven Haney -- Informatics considerations / Jay Copeland, Caroline Shamu -- Basic high content assay development / Steven Haney, Doug Bowman -- Designing metrics for high content assays / Arijit Chakravarty, Steven Haney, Doug Bowman -- Analyzing well-level data / Steven Haney, Arijit Chakravarty -- Analyzing cell level data / Steven Haney, Lin Guey, Arijit Chakravarty -- Designing robust assays / Arijit Chakrivarty, Doug Bowman, Anthony Davies, Caroline Shamu -- Automation and screening / John Donovan, Arijit Chakravarty, Anthony Davies, Steven Haney, Doug Bowman, John Ringling, Ben Knight -- High content analysis for tissue samples / Kristine Burke, Vaishali Sinde, Alice McDonald, Doug Bowman, Arijit Chakrivarty -- Factoring and clustering high content data / Steven Haney, Arijit Chakravarty -- Supervised machine learning / Jeff Palmer, Arijit Chakravarty. 
588 0 |a Print version record and CIP data provided by publisher. 
520 |a Using a collaborative and interdisciplinary author base withexperience in the pharmaceutical industry and academia, this book is a practical resource for high content (HC) techniques. Instructs readers on the fundamentals of highcontent screening (HCS) techniques ; Focuses on practical and widely-used techniques likeimage processing and multiparametric assays ; Breaks down HCS into individual modules for trainingand connects them at the end. Includes a tutorial chapter that works through sampleHCS assays, glossary, and detailed appendices. 
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650 0 |a Drugs  |x Analysis. 
650 0 |a Drug development. 
650 0 |a Drugs  |x Design. 
650 0 |a Biological models. 
650 2 |a Drug Design 
650 2 |a Systems Biology  |x methods 
650 2 |a Data Interpretation, Statistical 
650 2 |a Drug Evaluation, Preclinical  |x methods 
650 2 |a Image Processing, Computer-Assisted  |x methods 
650 2 |a Models, Biological 
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650 7 |a Drug development  |2 fast 
650 7 |a Drugs  |x Analysis  |2 fast 
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700 1 |a Haney, Steven A.,  |e editor. 
700 1 |a Bowman, Doug,  |d active 2014,  |e editor. 
700 1 |a Chakravarty, Arijit,  |e editor. 
700 1 |a Davies, Anthony,  |d active 2014,  |e editor. 
700 1 |a Shamu, Caroline,  |e editor. 
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