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The Ubiquitin-Proteasome Proteolytic System : From Classical Biochemistry to Human Diseases.

Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transp...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Ciechanover, Aaron J.
Otros Autores: Masucci, Maria G.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : World Scientific Publishing Company, 2002.
Colección:Recent advances in human biology.
Temas:
Acceso en línea:Texto completo

MARC

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049 |a UAMI 
100 1 |a Ciechanover, Aaron J. 
245 1 4 |a The Ubiquitin-Proteasome Proteolytic System :  |b From Classical Biochemistry to Human Diseases. 
260 |a Singapore :  |b World Scientific Publishing Company,  |c 2002. 
300 |a 1 online resource (240 pages) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Recent Advances in Human Biology 
588 0 |a Print version record. 
520 |a Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, endocytosis, stress responses, antigen presentation and other aspects of the immune response, the functions of the nervous system including circadian rhythms, axon guidance and acquisition of memory. This book tells the story of the ubiquitin system as we currently know it: from the regulation. 
505 0 |a Preface ; The Ubiquitin System and Some of Its Roles in Cell Cycle Control ; References ; The Ubiquitin System and the N-End Rule Pathway ; Summary ; The Ubiquitin System ; The N-End Rule Pathway ; Physical Association of Ubiquitin Ligases and the 26S Proteasome. 
505 8 |a Peptide Import and the N-End Rule Pathway The N-End Rule Pathway and Fidelity of Chromosome Segregation ; Concluding Remarks ; References ; Phosphorylation-Dependent Substrate Recognition in Ubiquitin-Mediated Proteolysis ; Abstract. 
505 8 |a Modular Protein Interaction Domains Regulate Dynamic Cellular Behaviour Protein-Protein Interactions Determine Specificity in Ubiquitin-Mediated Proteolysis ; Cdk Activity and the Control of DNA Replication ; Discovery of SCF Ubiquitin Ligases. 
505 8 |a Phosphorylation-Dependent Substrate Recognition by SCF Complexes Conservation of SCF Function in the Cell Cycle ; The Cdc4 Phospho-Degron ; Multi-Site Phosphorylation and Ultrasensitivity ; The Sicl-Cdc4 Interaction: Theoretical Considerations ; Discussion ; Prospects ; References. 
505 8 |a The 26S Proteasome: A Supramolecular Assembly Designed for Controlled Proteolysis Introduction ; Structural Features of the 26S Proteasome ; Conclusions ; References ; Mechanisms and Regulation of Ubiquitin-Mediated Limited Processing of the NF-kBa Precursor Protein p105 ; Summary. 
504 |a Includes bibliographical references. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Proteins  |x Metabolism. 
650 0 |a Proteolytic enzymes. 
650 0 |a Ubiquitin. 
650 0 |a Enzymes. 
650 0 |a Proteins. 
650 0 |a Hydrolases. 
650 0 |a Cysteine proteinases. 
650 0 |a Multienzyme complexes. 
650 2 |a Ubiquitin 
650 2 |a Endopeptidases 
650 2 |a Cysteine Proteases 
650 2 |a Multiprotein Complexes 
650 2 |a Enzymes 
650 2 |a Ubiquitins 
650 2 |a Enzymes and Coenzymes 
650 2 |a Peptide Hydrolases 
650 2 |a Proteins 
650 2 |a Macromolecular Substances 
650 2 |a Hydrolases 
650 2 |a Chemicals and Drugs 
650 2 |a Amino Acids, Peptides, and Proteins 
650 2 |a Cysteine Endopeptidases 
650 2 |a Multienzyme Complexes 
650 6 |a Protéines  |x Métabolisme. 
650 6 |a Enzymes protéolytiques. 
650 6 |a Ubiquitine. 
650 6 |a Endopeptidases. 
650 6 |a Enzymes. 
650 6 |a Protéines. 
650 6 |a Hydrolases. 
650 6 |a Peptidases à cystéine. 
650 6 |a Complexes multienzymatiques. 
650 7 |a enzyme.  |2 aat 
650 7 |a protein.  |2 aat 
650 7 |a Proteins  |2 fast 
650 7 |a Multienzyme complexes  |2 fast 
650 7 |a Hydrolases  |2 fast 
650 7 |a Enzymes  |2 fast 
650 7 |a Cysteine proteinases  |2 fast 
650 7 |a Proteins  |x Metabolism  |2 fast 
650 7 |a Proteolytic enzymes  |2 fast 
650 7 |a Ubiquitin  |2 fast 
700 1 |a Masucci, Maria G. 
776 0 8 |i Print version:  |z 9789812381002 
830 0 |a Recent advances in human biology. 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=1679423  |z Texto completo 
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994 |a 92  |b IZTAP