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Outstanding Marine Molecules.
Using a number of outstanding examples, this text introduces readers to the immense variety of marine natural compounds, the methodologies to characterize them and the approaches to explore their industrial potential. Care is also taken to discuss the function and ecological context of the compounds...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
Wiley,
2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Outstanding Marine Molecules: Chemistry, Biology, Analysis; Contents; List of Contributors; Foreword; Preface; Part One: Outstanding Marine Molecules from a Chemical Point of View; 1 Marine Cyanotoxins Potentially Harmful to Human Health; 1.1 Introduction; 1.2 Marine Cyanobacteria as Causative Agent of Ciguatera-Like Poisoning; 1.2.1 Ciguatera Fish Poisoning; 1.2.2 Ciguatera Shellfish Poisoning (CSP): A New Ecotoxicological Phenomenon; 1.2.3 Ciguatera-Like Poisonings Involve Complex Mixtures of Cyanotoxins; 1.2.3.1 Ciguatoxins and Homoanatoxin; 1.2.3.2 Ciguatoxins and Saxitoxins.
- 1.2.3.3 Ciguatoxins and Palytoxins1.3 Marine Cyanobacteria: A Potential Risk for Swimmers; 1.4 Microcystins Could also be Found in the Sea; 1.5 Risk of Neurodegenerative Disease in the Sea; 1.6 Conclusion and Future Prospects; Acknowledgments; References; 2 Outstanding Marine Biotoxins: STX, TTX, and CTX; 2.1 Introduction; 2.2 Saxitoxins (STXs) in Paralytic Shellfish Poisoning; 2.2.1 Causes of Paralytic Shellfish Poisoning; 2.2.2 Saxitoxins (STXs); 2.2.2.1 Chemical Aspects of the STXs; 2.2.2.2 Detection of PSP Toxins; 2.2.2.3 Poisoning Records.
- 2.3 Tetrodotoxin (TTX) in Puffer Fish Poisoning (PFP)2.3.1 Puffer Fish Poisoning (PFP); 2.3.1.1 Chemical Aspects of TTX; 2.3.1.2 Detection of TTXs; 2.4 Ciguatoxin (CTX) in Ciguatera Fish Poisoning (CFP); 2.4.1 Ciguatera Fish Poisoning (CFP); 2.4.2 Ciguatoxins; 2.4.2.1 Chemical Aspects; 2.4.2.2 Detection of CTX Toxins; 2.4.2.3 Poisoning Records; 2.4.2.4 Persistence and Recurrence of Symptoms; 2.4.2.5 Fish Containing Ciguatoxins; 2.4.2.6 Qualitative and Quantitative Methods for Toxins Detection; 2.5 Conclusions; References.
- 3 Impact of Marine-Derived Penicillium Species in the Discovery of New Potential Antitumor Drugs3.1 Introduction; 3.2 Molecules Isolated from Marine-Derived Penicillium Species With Potent Cytotoxic Activity; 3.3 Marine-Derived Cytotoxic Penicillium; 3.3.1 Where Were Marine-Derived Penicillium Searched and Isolated?; 3.3.2 Which Penicillium Species?; 3.4 What are these Promising Molecules from Marine Penicillium?; 3.4.1 Statistics; 3.4.2 Focus on Interesting Molecules; 3.4.2.1 Cytotoxic Alkaloids: The Example of Communesins.
- 3.4.3 Cytotoxic Alkaloids/Diketopiperazine Compounds: Examples of Fructigenine A and Verticillin Derivatives3.4.3.1 Fructigenine A (= Rugulosovin B = Puberulin); 3.4.3.2 Verticillin A and Derivatives; 3.4.4 Cytotoxic Sesquiterpenes: Ligerin, a Chlorinated Sesquiterpene; 3.4.4.1 Ligerin is Produced by a New Species of Penicillium; 3.4.4.2 Isolation of Ligerin; 3.4.4.3 The Chlorine Atom: The Originality of Ligerin's Chemical Structure; 3.4.4.4 The Many Structural Analogs of Ligerin; 3.4.4.5 Ligerin Semisynthesis; 3.4.4.6 Bioactivities; 3.5 Conclusions; References.