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The Biostatistics of Aging : From Gompertzian Mortality to an Index of Aging-Relatedness.
A practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion-with consequential biomedical and public h...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
Wiley,
2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Levy, Gilberto. | |
| 245 | 1 | 4 | |a The Biostatistics of Aging : |b From Gompertzian Mortality to an Index of Aging-Relatedness. |
| 260 | |a Hoboken : |b Wiley, |c 2014. | ||
| 300 | |a 1 online resource (270 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a THE BIOSTATISTICS OF AGING: From Gompertzian Mortalitytoan Index of Aging-Relatedness; Copyright; CONTENTS; PREFACE AND ACKNOWLEDGMENT; 1 Introduction; 2 An Account of Gompertzian Mortality through Statisticaland Evolutionary Arguments; 2.1 The Statistical Theory of Extreme Values; 2.1.1 Background to Results; 2.1.2 Original Results; 2.2 The Evolutionary Theory of Aging; 2.2.1 The Argument for Gompertzian Mortality; 2.2.2 Boundaries of the Argument; 3 The Argument against Gompertzian Mortality; 3.1 Departures from the Gompertz Model; 3.2 An Evolution-Based Model of Causation. | |
| 505 | 8 | |a 4 The Index of Aging-Relatedness4.1 A Survival Mixture Model of the Gompertz and WeibullDistributions; 4.2 Definition and Interpretation of the Index of Aging-Relatedness; 4.3 The Survival Mixture Model and Competing Risks; 4.4 Estimation of the Model Parameters; 4.5 Illustrative Application: The Israeli Ischemic Heart Disease Study; 4.6 Precision of Estimation; 5 Discussion: Implications; 5.1 The Meaning of the Gompertz Parameter; 5.2 Age as a Risk Factor for Disease; 5.3 Are Aging-Related Diseases an Integral Part of Aging?; 5.4 Biological versus Chronological Aging. | |
| 505 | 8 | |a 5.5 The Public Health Notion of Compression of Morbidity5.6 A Picture of Aging for the Twenty-First Century; APPENDIX A: PROOFS OF RESULTS IN SECTION 2.1.2 WITHSOME EXTENSIONS; APPENDIX B: DERIVATION OF HAMILTON'S EQUATIONFOR THE FORCE OF NATURAL SELECTIONON MORTALITY; APPENDIX C: SOME PROPERTIES OF THE GOMPERTZ ANDWEIBULL DISTRIBUTIONS; APPENDIX D: FIRST AND SECOND PARTIAL DERIVATIVES OFTHE MIXTURE LOG-LIKELIHOOD FUNCTION; APPENDIX E: EXPECTATION-CONDITIONAL MAXIMIZATION(ECM) ALGORITHM; APPENDIX F: R PROGRAM; REFERENCES; AUTHOR INDEX; SUBJECT INDEX. | |
| 520 | |a A practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion-with consequential biomedical and public health relevance-of what it means for acondition to be related to aging. In this pursuit, the book presents a new quantitative methodto examine the relative contributions of genetic and environmental factors to mortality anddisease incidence in a population. With input fr. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Aging |x Statistical methods. | |
| 650 | 0 | |a Mortality |x Statistical methods. | |
| 650 | 0 | |a Life spans (Biology) | |
| 650 | 0 | |a Life expectancy. | |
| 650 | 0 | |a Mortality. | |
| 650 | 1 | 2 | |a Aging |x pathology |
| 650 | 2 | 2 | |a Epidemiologic Methods |
| 650 | 2 | 2 | |a Life Expectancy |
| 650 | 2 | 2 | |a Models, Statistical |
| 650 | 2 | 2 | |a Mortality |
| 650 | 6 | |a Vieillissement |x Méthodes statistiques. | |
| 650 | 6 | |a Mortalité |x Méthodes statistiques. | |
| 650 | 6 | |a Durée de vie (Biologie) | |
| 650 | 6 | |a Espérance de vie. | |
| 650 | 6 | |a Mortalité. | |
| 650 | 7 | |a mortality. |2 aat | |
| 650 | 7 | |a Mortality |2 fast | |
| 650 | 7 | |a Life expectancy |2 fast | |
| 650 | 7 | |a Aging |x Statistical methods |2 fast | |
| 650 | 7 | |a Life spans (Biology) |2 fast | |
| 650 | 7 | |a Mortality |x Statistical methods |2 fast | |
| 700 | 1 | |a Levin, Bruce. | |
| 758 | |i has work: |a The biostatistics of aging (Text) |1 https://id.oclc.org/worldcat/entity/E39PCH4cJqrwPp3PW4CmFpRcbm |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Levy, Gilberto. |t Biostatistics of Aging : From Gompertzian Mortality to an Index of Aging-Relatedness. |d Hoboken : Wiley, ©2014 |z 9781118645857 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=1632617 |z Texto completo |
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