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Genome-based diagnostics : demonstrating clinical utility in oncology : workshop summary /

"Genome-Based Diagnostics: Demonstrating Clinical Utility in Oncology is the summary of a workshop convened in May 2012 by the Roundtable on Translating Genomic-Based Research for Health and the Center for Medical Technology Policy of the Institute of Medicine to foster the identified need for...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: Evidence for Clinical Utility of Molecular Diagnostics in Oncology (Workshop) Washington, D.C.)
Otros Autores: Berger, Adam C. (rapporteur.), Olson, Steve, 1956- (rapporteur.)
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press, 2013.
Temas:
Acceso en línea:Texto completo

MARC

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111 2 |a Evidence for Clinical Utility of Molecular Diagnostics in Oncology (Workshop)  |d (2012 :  |c Washington, D.C.) 
245 1 0 |a Genome-based diagnostics :  |b demonstrating clinical utility in oncology : workshop summary /  |c Adam C. Berger and Steve Olson, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies. 
264 1 |a Washington, D.C. :  |b National Academies Press,  |c 2013. 
300 |a 1 online resource (xix, 101 pages) :  |b illustrations 
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520 |a "Genome-Based Diagnostics: Demonstrating Clinical Utility in Oncology is the summary of a workshop convened in May 2012 by the Roundtable on Translating Genomic-Based Research for Health and the Center for Medical Technology Policy of the Institute of Medicine to foster the identified need for further sustained dialogue between stakeholders regarding the clinical utility of molecular diagnostics. The workshop brought together a wide range of stakeholders, including patients, health care providers, policy makers, payers, diagnostic test developers, researchers, and guideline developers, to identify the challenges and opportunities in advancing the development and use of molecular diagnostic tests designed to guide the treatment and management of patients with cancer. The sequencing of the human genome has greatly accelerated the process of linking specific genetic variants with disease. These findings have yielded a rapidly increasing number of molecular diagnostic tests designed to guide disease treatment and management. Many of these tests are aimed at determining the best treatments for specific forms of cancer, making oncology a valuable testing ground for the use of molecular diagnostic tests in medicine in general. Nevertheless, many questions surround the clinical value of molecular diagnostic tests, and their acceptance by clinicians, payers, and patients has been unpredictable. A major limiting factor for the use of these tests has been the lack of clear evidence of clinical utility. Genome-Based Diagnostics assesses the evidentiary requirements for clinical utility of molecular diagnostics used to guide treatment decisions for patients with cancer; discusses methodologies related to demonstrating these evidentiary requirements that meet the needs of all stakeholders; and considers innovative, sustainable research collaborations for generating evidence of clinical utility involving multiple stakeholders"--Publisher's description 
504 |a Includes bibliographical references. 
505 0 |a Introduction -- Setting the context -- Perspectives from stakeholders -- Tools for generating and synthesizing evidence -- Advancing molecular diagnostics for oncology. 
588 0 |a Online resource; title from resource home page (National Academies Press, viewed April 23, 2014). 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Molecular diagnosis  |v Congresses. 
650 0 |a Cancer  |x Molecular diagnosis  |v Congresses. 
650 1 2 |a Molecular Diagnostic Techniques 
650 1 2 |a Neoplasms  |x diagnosis 
650 6 |a Diagnostics moléculaires  |v Congrès. 
650 6 |a Cancer  |x Diagnostic moléculaire  |v Congrès. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Cancer  |x Molecular diagnosis  |2 fast 
650 7 |a Molecular diagnosis  |2 fast 
655 2 |a Congress 
655 7 |a proceedings (reports)  |2 aat 
655 7 |a Conference papers and proceedings  |2 fast 
655 7 |a Conference papers and proceedings.  |2 lcgft 
655 7 |a Actes de congrès.  |2 rvmgf 
700 1 |a Berger, Adam C.,  |e rapporteur. 
700 1 |a Olson, Steve,  |d 1956-  |e rapporteur.  |1 https://id.oclc.org/worldcat/entity/E39PBJpV6yX9jFKMQMYFvVkhpP 
710 2 |a Institute of Medicine (U.S.).  |b Roundtable on Translating Genomic-Based Research for Health,  |e issuing body. 
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776 0 8 |i Print version:  |t Genome-based diagnostics.  |d Washington, D.C. : National Academy Press, [2013]  |z 9780309269599  |w (OCoLC)869266322 
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