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Control and Surveillance of Human African Trypanosomiasis : Report of a WHO Expert Committee.
This report provides information about new diagnostic approaches new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping. The roles of human and animal reservoirs and the tsetse fly vectors that transmit the parasites are emphasized. The new inf...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Geneva :
World Health Organization,
2013.
©2013 |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Contents; Abbreviations and acronyms; WHO Expert Committee on control and surveillance of human African trypanosomiasis; 1. Introduction; 2. Epidemiology of human African trypanosomiasis; 2.1 Two diseases, two parasites, two epidemiological patterns; 2.2 Transmission cycle; 2.2.1 Gambiense human African trypanosomiasis; 2.2.2 Rhodesiense human African trypanosomiasis; 2.3 Reservoirs of infection; 2.3.1 Gambiense human African trypanosomiasis; 2.3.2 Rhodesiense human African trypanosomiasis; 2.4 Risk factors for infection; 2.4.1 Gambiense human African trypanosomiasis.
- 2.4.2 Rhodesiense human African trypanosomiasis2.5 Trends in numbers of cases reported; 2.5.1 Gambiense human African trypanosomiasis; 2.5.2 Rhodesiense human African trypanosomiasis; 2.6 Geographical distribution and population at risk; 2.7 Global environmental change; 2.8 References; 3. The parasite; 3.1 Taxonomy of human infectious African trypanosomes; 3.2 Morphology and cell structure; 3.3 Life-cycle; 3.4 The Trypanosoma brucei genome; 3.5 Immune evasion; 3.6 Biochemistry and modes of drug action; 3.7 Drug resistance; 3.8 References; 4. The vector; 4.1 Classification.
- 4.1.1 Subgenus Nemorhina4.1.2 Subgenus Glossina s. str.; 4.1.3 Subgenus Austenina; 4.2 Reproductive system; 4.3 Reproduction; 4.4 Lifespan and population dynamics; 4.5 Diet; 4.6 Geographical distribution of the main vector species; 4.6.1 Vector species of the Nemorhina subgenus; 4.6.2 Vector species of the Glossina s. str. subgenus; 4.6.3 Vector species of the Austenina subgenus; 4.7 Tsetse flies in their natural environment; 4.7.1 Main habitats; 4.7.2 Movements; 4.7.3 Looking for hosts; 4.7.4 Feeding preferences; 4.7.5 Activity cycles; 4.7.6 Dispersal; 4.7.7 Resting places.
- 4.8 Population genetics and geometric morphometrics4.9 Genomics of tsetse flies; 4.10 Tsetse flies as cyclical vectors; 4.11 Vector control strategies; 4.11.1 Control; 4.11.2 Eradication; 4.11.3 Preliminary surveys; 4.12 Tsetse fly control methods; 4.12.1 Bush clearing; 4.12.2 Elimination of wild animal hosts; 4.12.3 Biological control of tsetse flies; 4.12.4 Autonomous control of tsetse flies; 4.12.5 Indigenous tsetse fly control practices; 4.12.6 Ground and aerial insecticide spraying; 4.12.7 Protecting zero grazing units by insecticide-impregnated netting; 4.12.8 Bait methods.
- 4.12.9 Olfactory baits (attractants) for tsetse flies4.12.10 Live baits; 4.12.11 Sterile insect technique; 4.13 New developments and outlook; 4.14 References; 5. The disease; 5.1 Gambiense human African trypanosomiasis: clinical signs and symptoms; 5.1.1 Lymphadenopathy; 5.1.2 Fever; 5.1.3 Headache; 5.1.4 Pruritus; 5.1.5 Musculoskeletal pain, hepatomegaly and splenomegaly; 5.1.6 Cardiac involvement; 5.1.7 Gastrointestinal symptoms; 5.1.8 Oedema; 5.1.9 Sleep disorder; 5.1.10 Neuropsychiatric symptoms and signs; 5.1.11 Endocrine disorders.