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LEADER 00000cam a2200000Ma 4500
001 EBOOKCENTRAL_ocn866839740
003 OCoLC
005 20240329122006.0
006 m o d
007 cr |n|||||||||
008 131227s2014 gw ob 001 0 eng d
040 |a IDEBK  |b eng  |e pn  |c IDEBK  |d EBLCP  |d DG1  |d YDXCP  |d RECBK  |d OCLCF  |d OCLCQ  |d DEBSZ  |d DEBBG  |d OCLCQ  |d DG1  |d SCB  |d LIP  |d ZCU  |d MERUC  |d OCLCQ  |d VT2  |d OCLCO  |d OCLCQ  |d MERER  |d U3W  |d OCLCQ  |d DKC  |d OCLCQ  |d UKAHL  |d OCLCQ  |d OCLCA  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCL 
019 |a 1055395455  |a 1081207952 
020 |a 9783527675272  |q (oBook) 
020 |a 3527675272  |q (oBook) 
020 |a 9783527675296  |q (ePDF) 
020 |a 3527675299  |q (ePDF) 
020 |a 1306256178  |q (electronic bk.) 
020 |a 9781306256179  |q (electronic bk.) 
020 |z 9783527333172  |q (print) 
020 |z 3527333177  |q (print) 
020 |z 9783527675289  |q (epub) 
020 |z 9783527675302  |q (mobi) 
029 1 |a AU@  |b 000061128797 
029 1 |a CHNEW  |b 000942655 
029 1 |a CHVBK  |b 480229473 
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029 1 |a DEBSZ  |b 485044544 
029 1 |a GBVCP  |b 790211157 
029 1 |a NZ1  |b 15495744 
035 |a (OCoLC)866839740  |z (OCoLC)1055395455  |z (OCoLC)1081207952 
037 |a 556868  |b MIL 
050 4 |a RS431.P38 
050 4 |a RS420  |b .C384 2013 
060 4 |a 2014 D-270 
060 4 |a QU 55 
082 0 4 |a 615.3  |2 23 
082 0 4 |a 613.5 
049 |a UAMI 
245 0 0 |a Therapeutic Fc Fusion Proteins /  |c edited by Steven M. Chamow [and others]. 
260 |a Weinheim :  |b Wiley-Blackwell,  |c ©2014. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
505 0 |a Introduction: Antibody Structure and Function / Arvind Rajpal, Pavel Strop, Yik Andy Yeung, Javier Chaparro-Riggers, Jaume Pons -- Methods of Production for Fc-Fusion Proteins. Fc-Fusion Protein Expression Technology / Jody D Berry, Catherine Yang, Janean Fisher, Ella Mendoza, Shanique Young, Dwayne Stupack -- Cell Culture-Based Production / Yao-Ming Huang, Rashmi Kshirsagar, Barbara Woppmann, Thomas Ryll -- Downstream Processing of Fc-Fusion Proteins / Abhinav A Shukla, Uwe Gottschalk -- Formulation, Drug Product, and Delivery: Considerations for Fc-Fusion Proteins / Wenjin Cao, Deirdre Murphy Piedmonte, Margaret Speed Ricci, Ping Y Yeh -- Quality by Design Applied to a Fc-Fusion Protein: A Case Study / Alex Eon-Duval, Ralf Gleixner, Pascal Valax, Miroslav Soos, Benjamin Neunstoecklin, Massimo Morbidelli, Hervé Broly -- Analytical Methods Used to Characterize Fc-Fusion Proteins / Esohe Idusogie, Michael Mulkerrin -- Case Studies of Therapeutic Fc-Fusion Proteins. Introduction to Therapeutic Fc-Fusion Proteins / Jody D Berry -- Alefacept / Deborah A Farson -- Etanercept / Johanna Grossman, Steven M Chamow -- Abatacept and Belatacept / Robert J Peach -- Aflibercept / Angela L Linderholm, Steven M Chamow -- Recombinant Factor VIII- and Factor IX-Fc Fusions / Robert T Peters, Judy R Berlfein. 
500 |a Includes index. 
588 0 |a Print version record. 
504 |a Includes bibliographical references and index. 
520 8 |a Annotation  |b Edited by three pioneers in the field - each with longstanding experience in the biotech industry - and a skilled scientific writer, this is the first book to cover every step in the development and production of immunoglobulin Fc-fusion proteins as therapeutics for human disease: from choosing the right molecular design, to pre-clinical characterization of the purified product, through to batch optimization and quality control for large-scale cGMP production. The whole of the second part is devoted to case studies of Fc-fusion proteins that are now commercially successful products. In this section, the authors, several of whom were personally involved in clinical development of the products themselves, detail the product's background and give insight into issues that were faced and how these issues were overcome during clinical development. This section also includes a chapter on promising new developments for the future. An invaluable resource for professionals already working on Fc-fusion proteins and an excellent and thorough introduction for physicians, researchers, and students entering the field. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Peptide drugs. 
650 0 |a Proteins. 
650 0 |a Proteins  |x Synthesis. 
650 1 2 |a Recombinant Fusion Proteins  |x therapeutic use 
650 1 2 |a Immunoglobulin Fc Fragments  |x therapeutic use 
650 1 2 |a Recombinant Fusion Proteins  |x pharmacology 
650 1 2 |a Immunoglobulin Fc Fragments  |x pharmacology 
650 2 |a Proteins 
650 2 |a Protein Biosynthesis 
650 6 |a Médicaments peptidiques. 
650 6 |a Protéines. 
650 6 |a Protéines  |x Synthèse. 
650 7 |a protein.  |2 aat 
650 7 |a Peptide drugs  |2 fast 
650 7 |a Proteins  |2 fast 
650 7 |a Proteins  |x Synthesis  |2 fast 
700 1 |a Chamow, Steven Mark. 
758 |i has work:  |a Therapeutic Fc Fusion Proteins (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGK43R7MpYpKcrRf4DcCDC  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |z 9781306256179 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=1583680  |z Texto completo 
938 |a Askews and Holts Library Services  |b ASKH  |n AH25969462 
938 |a Askews and Holts Library Services  |b ASKH  |n AH25969463 
938 |a EBL - Ebook Library  |b EBLB  |n EBL1583680 
938 |a ProQuest MyiLibrary Digital eBook Collection  |b IDEB  |n cis27167997 
938 |a Recorded Books, LLC  |b RECE  |n rbeEB00174043 
938 |a YBP Library Services  |b YANK  |n 11072925 
994 |a 92  |b IZTAP