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|a UAMI
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|a Textbook of organ transplantation /
|c editors, Allan D. Kirk, Stuart J. Knechtle, Christian P. Larsen, Thomas C. Pearson, Joren C. Madsen, Steven A. Webber.
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264 |
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1 |
|a Chichester, West Sussex :
|b John Wiley & Sons, Inc.,
|c 2014.
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300 |
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|a 1 online resource
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336 |
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|a text
|b txt
|2 rdacontent
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|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Includes bibliographical references and index.
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588 |
0 |
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|a Print version record and CIP data provided by publisher.
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|a Cover; Title page; Copyright page; Contents; List of Contributors; Volume 1; SECTION 1: History/Introduction; Introduction; CHAPTER 1: A Brief History of Clinical Organ Transplantation; Introduction; The concept of transplant surgery; Transplant biology; Early clinical implementation; The modern era of immune management; Ethical challenges; Summary; References; SECTION 2: Transplantation Biology; Immunology; CHAPTER 2: An Overview of Physiologic Immunity; Introduction; Generalized protective barriers and defense factors; Tissues and organs of the immune system.
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|a Cells of the innate and adaptive immune systemInnate immune cells; Granulocytes; Natural killer (NK) cells; Mononuclear phagocytes; Adaptive immune cells; T-cell immunobiology; CD8+ T cells; CD4+ T cells; Need for APC costimulation for T-cell activation; The cytokine milieu and Th-cell polarization; T-cell plasticity; B-cell immunobiology; B-cell activation; The complement system; Cytokines; Structural features and categories (families) of cytokines; The importance of cytokines; Synergistic and antagonistic interactions; Stimulatory and inhibitory properties of cytokines.
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8 |
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|a Redundancy and pleiotropyImmunological tolerance; T-cell central tolerance; T-cell peripheral tolerance; B-cell central tolerance; B-cell peripheral tolerance; Immunological memory; T-cell memory; B-cell memory; Summary; Acknowledgments; References; CHAPTER 3: Transplant Antigens: A Brief History of HLA; Introduction; Early investigations; HLA and disease; HLA and transplantation; HLA antibodies; Summary; References; CHAPTER 4: Transplant Antigen Biology; Introduction; Genetics of the major histocompatibility complex (MHC); MHC class I; MHC class II; MHC class III; Nature of HLA polymorphism.
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505 |
8 |
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|a Human diversity in HLA repertoireHLA nomenclature; HLA epitopes and the structural basis of cross-reactivity; Structure and function of HLA molecules; HLA class I molecular structure; HLA class II molecular structure; Structural basis of peptide binding to HLA class I and class II molecules; Antigen processing and presentation; Differential expression of HLA class I and class II molecules; HLA Class Ib molecules; HLA-mediated signal transduction; Killer cell immunoglobulin-like receptors (KIR); Non-HLA transplant antigens; Anti-MICA antibodies; Summary; Acknowledgments; References.
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505 |
8 |
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|a CHAPTER 5: Cellular Mechanisms of Adaptive ImmunityIntroduction; T-cell recognition of alloantigens: Direct, semidirect, and indirect presentation; Structural recognition of alloantigens by the TCR; T-cell costimulation and differentiation; Innate immune signals that influence T-cell responses; Where are T cells primed after transplantation?; Effector phase of the alloimmune response: T cells go to the graft; Effector T cells: Th1, Th2, Th17, and cytotoxic T cells; Therapeutic implications; Summary; Acknowledgments; References; CHAPTER 6: Humoral Mechanisms of Adaptive Immunity; Introduction.
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520 |
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|a Brought to you by the world's leading transplant clinicians, Textbook of Organ Transplantation providesa complete and comprehensive overview of modern transplantation in all its complexity, from basic science to gold-standard surgical techniques to post-operative care, and from likely outcomes to considerations for transplant program administration, bioethics and health policy. Beautifully produced in full color throughout, and with over 600 high-quality illustrations, it successfully: Provides a solid overview of what transplant clinicians/surgeons do, and with topics presented in an order.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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0 |
|a Transplantation of organs, tissues, etc.
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650 |
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2 |
|a Organ Transplantation
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650 |
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6 |
|a Greffe (Chirurgie)
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650 |
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7 |
|a Transplantation of organs, tissues, etc.
|2 fast
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700 |
1 |
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|a Kirk, Allan,
|e editor.
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776 |
0 |
8 |
|i Print version:
|t Textbook of organ transplantation.
|d Chichester, West Sussex : John Wiley & Sons, Inc., 2014
|z 9781118870143
|w (DLC) 2013049540
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856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=1752705
|z Texto completo
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938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL4039569
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994 |
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|a 92
|b IZTAP
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