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| 001 |
EBOOKCENTRAL_ocn865508451 |
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OCoLC |
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20240329122006.0 |
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m o d |
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cr cnu---unuuu |
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131217s1996 nyua ob 001 0 eng d |
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|b eng
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|a 3110808900
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|a 10.1515/9783110808902
|2 doi
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|a dlr
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|b .C64 1996eb
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|a 1996 C-247
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|a QU 58
|b C731 1996
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|b 1996
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|0 (DE-625)rvk/148102:
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| 049 |
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|a UAMI
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| 245 |
0 |
0 |
|a Combinatorial libraries :
|b synthesis, screening, and application potential /
|c editor, Riccardo Cortese.
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| 264 |
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1 |
|a New York :
|b Walter de Gruyter,
|c 1996.
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| 300 |
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|a 1 online resource (xii, 232 pages) :
|b illustrations
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 504 |
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|a Includes bibliographical references and index.
|
| 506 |
|
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|3 Use copy
|f Restrictions unspecified
|2 star
|5 MiAaHDL
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| 533 |
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|a Electronic reproduction.
|b [Place of publication not identified] :
|c HathiTrust Digital Library,
|d 2010.
|5 MiAaHDL
|
| 538 |
|
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|a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
|u http://purl.oclc.org/DLF/benchrepro0212
|5 MiAaHDL
|
| 583 |
1 |
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|a digitized
|c 2010
|h HathiTrust Digital Library
|l committed to preserve
|2 pda
|5 MiAaHDL
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| 588 |
0 |
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|a Print version record.
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| 505 |
0 |
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|a Contents -- A Synthetic Peptide Libraries -- 1 Soluble Synthetic Combinatorial Libraries: The Use of Molecular Diversities for Drug Discovery -- 1.1 Introduction -- 1.2 Synthetic Combinatorial Libraries (SCLs) -- 1.3 Synthetic Methods for the Generation of SCLs -- 1.4 SCLs in Drug Discovery and Basic Research -- 1.5 Conclusion -- 2 Combinatorial Libraries of Synthetic Structures: Synthesis, Screening, and Structure Determination -- 2.1 Introduction -- 2.2 One-Bead One-Structure Concept -- 2.3 Design and Synthesis of Non-Peptide Libraries -- 2.4 Release Assay
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| 505 |
8 |
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|a 2.5 Stucture Determination2.6 Conclusion -- 3 Peptide Libraries Bound to Continuous Cellulose Membranes: Tools to study Molecular Recognition -- 3.1 Introduction -- 3.2 Detection of antibody epitopes -- 3.3 Mutational analyses of peptide epitopes -- 3.4 Positional scanning combinatorial library -- 3.5 Indentification of metal binding peptides -- 3.6 Summary -- B Nucleic Acids Libraries -- 4 In Vitro Selection of Nucleic Acid Sequences that Bind Small Molecules -- 4.1 Introduction -- 4.2 Natural RNA Receptors -- 4.3 In Vitro Selection
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| 505 |
8 |
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|a 4.4 Amino Acid Aptamers4.5 Cofactors -- 4.6 DNA Aptamers -- 4.7 The Complexity of Complexity -- 4.8 Aptamer Structures -- 4.9 Transition State Stabilization and Tight Binding -- 4.10 Conclusions -- 5 Discovery and Characterization of a Thrombin Aptamer Selected from a Combinatorial ssDNA Library -- 5.1 Introduction -- 5.2 Discovery and Initial Characterization -- 5.3 Structure -- 5.4 Binding Site on Thrombin -- 5.5 Determination of Kd and Ki -- 5.6 In vitro Activity -- 5.7 In Vitro Activity -- 5.8 Conclusions -- C Phage Display of Peptide Libraries
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| 505 |
8 |
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|a 6 Structural and Functional Constraints in the Display of Peptides on Filamentous Phage Capsids6.1 Introduction -- 6.2 The Phage Life Cycle -- 6.3 A Low Resolution Model -- 6.4 Extending the Amino-Terminus of pVIII -- 6.5 Modifying the Surface of Filamentous Phage by Amino Acid Substitution -- 6.6 Can the Remaining Minor Proteins Support Modification? -- 7 Conformationally Defined Peptide Libraries on Phage: Selectable Templates for the Design of Pharmacological Agents -- 7.1 Introduction -- 7.2 From Peptides to Peptidomimetics
|
| 505 |
8 |
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|a 7.3 Building Constraints in Phage-Displayed Polypeptides7.4 The Minibody: An Engineered ß-Pleated Scaffold for the Display of Reverse-Turn Motifs -- 7.5 The Zinc Finger: A Small Domain for the Display of Structurally Homogeneous α-Helical Motifs -- 7.6 Future Developments: Progressing Toward Non-Peptide Pharmaceuticals -- 8 Discovery of Disease-Specific Mimotopes by Screening Phage Libraries with Human Serum Samples -- 8.1 Introduction -- 8.2 Using Polyclonal Antibodies as a Ligate for the Selection of RPL
|
| 546 |
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|a In English.
|
| 590 |
|
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
|
| 650 |
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0 |
|a Nucleotide sequence.
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| 650 |
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0 |
|a Amino acid sequence.
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| 650 |
|
0 |
|a Genetic vectors.
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| 650 |
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2 |
|a Base Sequence
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| 650 |
|
2 |
|a Amino Acid Sequence
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| 650 |
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2 |
|a Genetic Vectors
|
| 650 |
|
6 |
|a Séquence des acides aminés.
|
| 650 |
|
6 |
|a Vecteurs de clonage.
|
| 650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Biology.
|2 bisacsh
|
| 650 |
|
7 |
|a Amino acid sequence
|2 fast
|
| 650 |
|
7 |
|a Genetic vectors
|2 fast
|
| 650 |
|
7 |
|a Nucleotide sequence
|2 fast
|
| 650 |
|
7 |
|a Séquence nucléotidique.
|2 ram
|
| 650 |
|
7 |
|a Vecteurs de clonage.
|2 ram
|
| 650 |
|
7 |
|a Séquençage des acides aminés.
|2 ram
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| 700 |
1 |
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|a Cortese, Riccardo.
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| 758 |
|
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|i has work:
|a Combinatorial Libraries: Synthesis, Screening, and Application Potential (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCXY3XwYyVkVkk8yprddM6C
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
| 773 |
0 |
8 |
|i Druckausg.:
|t Combinatorial libraries.
|
| 776 |
0 |
8 |
|i Print version:
|t Combinatorial libraries
|z 311014395X
|w (DLC) 95039772
|w (OCoLC)33104050
|
| 856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=3045163
|z Texto completo
|
| 938 |
|
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|a De Gruyter
|b DEGR
|n 9783110808902
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|
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|a EBL - Ebook Library
|b EBLB
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| 938 |
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|a ebrary
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|n ebr10819933
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|a EBSCOhost
|b EBSC
|n 674026
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|a ProQuest MyiLibrary Digital eBook Collection
|b IDEB
|n cis27170089
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| 938 |
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|
|a Internet Archive
|b INAR
|n combinatoriallib0000unse_f2h3
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| 938 |
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|a YBP Library Services
|b YANK
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| 994 |
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|b IZTAP
|
