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The OMICs : Applications in Neuroscience.

The OMICs: Applications in Neuroscience summarizes the state of the art in high-throughput approaches (collectively known as 'OMICs') in neurology and neuroscience, and is of interest to both neurologists tracking the progress of these methods towards clinical applications, and neuroscient...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Coppola, Giovanni (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford : Oxford University Press, USA, 2013.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; THE OMICs; Copyright; CONTENTS; CONTRIBUTORS; PART ONE: DNA; 1. Medical DNA Sequencing in Neuroscience; 2 . Epigenomics: An Overview; 3. The Role of Epigenomics in Genetically Identical Individuals; PART TWO: RNA; 4. Transcriptomics; 5. Decoding Alternative mRNAs in the "Omics" Age; 6. Transcriptomics: From Differential Expression to Coexpression; 7. High-Throughput RNA Interference as a Tool for Discovery in Neuroscience; 8. The Genetics of Gene Expression: Multiple Layers and Multiple Players; PART THREE: PROTEIN; 9. Proteomics.
  • 10. Focused Plasma Proteomics for the Study of Brain Aging and NeurodegenerationPART FOUR: CELLS AND CONNECTIONS; 11. Cellomics: Characterization of Neural Subtypes by High-Throughput Methods and Transgenic Mouse Models; 12. Neuroscience and Metabolomics; 13. Brain Connectomics in Man and Mouse; 14. Optogenetics; 15. Characterizing the Gut Microbiome: Role in Brain-Gut Function; PART FIVE: THERAPEUTICS; 16. OMICs in Drug Discovery: From Small Molecule Leads to Clinical Candidates; 17. Pharmacogenomics; PART SIX: OMICsOME: INTEGRATION OF OMICs DATA.
  • 18. Multidimensional Databases of Model Organisms19. Network Biology and Molecular Medicine in the Postgenomic Era: The Systems Pathobiology of Network Medicine; Links to Helpful Resources; Index.