Cargando…

Equilibria and kinetics of biological macromolecules /

Equilibria and Kinetics of Biological Macromolecules provides readers with an understanding of the biophysics of macromolecules. Presentedwitha pedagogical approach, beginning with introductory concepts, the bookaddresses thermodynamics, statistical mechanics, ligand binding of proteins, and conform...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Lentz, Barry
Otros Autores: Hermans, Jan
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, N.J. : Wiley, 2013.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000Ma 4500
001 EBOOKCENTRAL_ocn864919047
003 OCoLC
005 20240329122006.0
006 m o d
007 cr cnu---unuuu
008 090713s2013 nju o 000 u eng d
040 |a RECBK  |b eng  |e pn  |c RECBK  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCQ  |d HEBIS  |d OCLCF  |d EBLCP  |d MHW  |d IDEBK  |d OCLCQ  |d ZCU  |d MERUC  |d OCLCQ  |d DKC  |d OCLCQ  |d SXB  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCL 
019 |a 861559760 
020 |a 9781118733776  |q (electronic bk.) 
020 |a 1118733770  |q (electronic bk.) 
028 0 1 |a EB00064190  |b Recorded Books 
035 |a (OCoLC)864919047  |z (OCoLC)861559760 
050 4 |a RM301.5 
060 1 0 |a QT 37 
082 0 4 |a 615.7 
049 |a UAMI 
100 1 |a Lentz, Barry. 
245 1 0 |a Equilibria and kinetics of biological macromolecules /  |c Barry Lentz and Jan Hermans. 
260 |a Hoboken, N.J. :  |b Wiley,  |c 2013. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
520 |a Equilibria and Kinetics of Biological Macromolecules provides readers with an understanding of the biophysics of macromolecules. Presentedwitha pedagogical approach, beginning with introductory concepts, the bookaddresses thermodynamics, statistical mechanics, ligand binding of proteins, and conformational stability, before focusing on focuses on kinetics and equilibria via discussion of discussion of theory, protein folding, and stochastic models. Placing a strong emphasis on molecular interactions, this reference also contains extensive appendices offer refreshers on probability, deriving grand partial functions, computational methods, helix-coil transition theory, laplace transformation, Poisson equation, defining molecular boundaries, and various equations, among other useful facts. 
500 |a Title from resource description page (Recorded Books, viewed November 21, 2013). 
505 0 |a Cover; Title Page; Copyright; Dedication; Preface; Chapter 1: Thermodynamics; 1.1 Introduction; 1.2 The Fundamental Postulates or Laws of Thermodynamics; 1.3 Other Useful Quantities and Concepts; 1.4 Thermodynamics of the Ideal Gas; 1.5 Thermodynamics of Solutions; 1.6 Phase Equilibria; 1.7 Chemical Equilibria; 1.8 Temperature Dependence of Chemical Equilibria: The Van't Hoff Equation; 1.9 Microcalorimetry; Chapter 2: Four Basic Quantum Mechanical Models of Nuclear and Electronic Motion: A Synopsis; 2.1 Introduction; 2.2 Fundamental Hypotheses of Quantum Theory. 
505 8 |a 2.3 Three Simple Models of Nuclear Motion2.4 Hydrogen Atomic Orbitals: A Simple Model of Electronic Motion in Atoms; 2.5 Many Electron Atoms; Suggested Reading; Chapter 3: Molecular Structure and Interactions; 3.1 Introduction; 3.2 Chemical Bonding: Electronic Structure of Molecules; 3.3 Empirical Classical Energy Expressions; 3.4 Noncovalent Forces Between Atoms and Molecules; 3.5 Molecular Mechanics; Suggested Reading; Chapter 4: Water and the Hydrophobic Effect; 4.1 Introduction; 4.2 Structure of Liquid Water; 4.3 THE HYDROPHOBIC EFFECT; Suggested Reading. 
505 8 |a Chapter 5: The Molecular Partition Function5.1 Introduction; 5.2 The Maxwell-Boltzmann Distribution; 5.3 The Molecular Partition Function and Thermodynamic Functions; 5.4 Application to Macromolecules; Suggested Reading; Chapter 6: System Ensembles and Partition Functions; 6.1 Introduction; 6.2 Closed Systems: The Canonical Ensemble; 6.3 The Canonical Partition Function of Systems with Continuous Energy Distributions: The Phase-Space Integral; 6.4 Application: Relation Between Binding and Molecular Interaction Energy; 6.5 Application: Binding of Ligand to a Macromolecule. 
505 8 |a 6.6 Open Systems: The Grand Canonical Ensemble or Grand Ensemble6.7 Fluctuations; 6.8 Application: Light Scattering as a Measure of Fluctuations of Concentration; Suggested Reading; Chapter 7: Sampling Molecular Systems with Simulations; 7.1 Introduction; 7.2 Background; 7.3 Molecular Dynamics; 7.4 Metropolis Monte Carlo; 7.5 Simulation of A Condensed System; 7.6 Connecting Microscopic and Macroscopic System Properties; 7.7 An Example: Dynamics of Ace-Ala-Nme in Solution; 7.8 Forced Transitions; 7.9 Potential of Mean Force for Changes of Chemistry: "Computer Alchemy." 
505 8 |a 7.10 The Potential of Mean Force and the Association Equilibrium Constant of MethaneSuggested Reading; Chapter 8: Binding Equilibria; 8.1 Introduction; 8.2 Single-Site Model; 8.3 Measuring Ligand Activity and Saturation; 8.4 Multiple Sites for a Single Ligand; 8.5 A Few Practical Recommendations; Suggested Reading; Chapter 9: Thermodynamics of Molecular Interactions; 9.1 Introduction; 9.2 Relation Between Binding and Chemical Potential: Unified Formulation of Binding and "Exclusion"; 9.3 Free Energy of Binding; 9.4 Mutual Response; 9.5 Volume Exclusion. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Science. 
650 2 |a Biocompatible Materials  |x pharmacokinetics 
650 2 |a Biophysical Phenomena 
650 2 |a Macromolecular Substances  |x pharmacokinetics 
650 2 |a Molecular Conformation 
650 2 |a Science 
650 6 |a Sciences. 
650 6 |a Phénomènes biophysiques. 
650 7 |a sciences (philosophy)  |2 aat 
650 7 |a science (modern discipline)  |2 aat 
650 7 |a SCIENCE  |x Life Sciences  |x Biochemistry.  |2 bisacsh 
650 7 |a Science  |2 fast 
700 1 |a Hermans, Jan. 
758 |i has work:  |a Equilibria and kinetics of biological macromolecules (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGWfjk8fF9cG6vhQYcDwRX  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Hermans, Jan.  |t Equilibria and Kinetics of Biological Macromolecules.  |d Hoboken : Wiley, ©2013  |z 9781118479704 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=1498522  |z Texto completo 
938 |a EBL - Ebook Library  |b EBLB  |n EBL4038178 
938 |a EBL - Ebook Library  |b EBLB  |n EBL1498522 
938 |a ProQuest MyiLibrary Digital eBook Collection  |b IDEB  |n cis26870101 
938 |a Recorded Books, LLC  |b RECE  |n rbeEB00064190 
994 |a 92  |b IZTAP