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Blockbuster Drugs : the Rise and Decline of the Pharmaceutical Industry.
Blockbuster drugs-each of which generates more than a billion dollars a year in revenue-have revolutionized the industry since the early 1980s, when sales of Tagamet alone transformed a minor Philadelphia-based firm into the world's ninth-largest pharmaceutical company. In Blockbuster Drugs, Ji...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Oxford University Press, USA,
2013.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Contents; Preface; 1. Before the Age of Blockbuster Drugs; 2. Beginning of an Era: The First Blockbuster; 2.1. James Black and the Discovery of Tagamet; 2.2. From a Frog into a Prince; 2.3. Zantac and More "Me-Toos"; 2.4. Lessons; 3. More Blockbuster Drugs for Ulcers: Prilosec, Nexium, and Other Proton-Pump Inhibitors; 3.1. Better Ulcer Drugs Still Needed; 3.2. Prilosec; 3.3. Nexium; 3.4. "Me-Too" Proton-Pump Inhibitors; 3.5. The Saga Continues-Ulcers Are Caused; 4. Antihistamines as Allergy Drugs; 4.1. What Causes Allergies?; 4.2. Conventional Antihistamines.
- 4.3. Second-Generation Antihistamines5. Blood Thinners: From Heparin to Plavix; 5.1. Tales of Two Old Drugs: Heparin and Warfarin; 5.2. Good Old Aspirin; 5.3. From Ugly Duckling to Beautiful Swan-From Ticlid to Plavix; 5.4. Blood Feud; 5.5. Beyond Plavix; 6. Conquest of Pain: Analgesics: From Morphine to Lyrica; 6.1. Aspirin and Other NSAIDs; 6.2. Celebrex and COX-2 Inhibitors; 6.3. Morphine and Opiates; 6.4. Fentanyl and Opioids; 6.5. Effexor and Other Antidepressants; 6.6. Parke-Davis and Dilantin; 6.7. Parke-Davis and Neurontin; 6.8. Silverman and His Theory on GABA Compounds.
- 6.9. Parke-Davis and Lyrica6.10. Lyrica, the Blockbuster Windfall; 6.11. How Does Lyrica Work, Exactly?; 7. Reflections; 7.1. What Makes a Blockbuster Drug?; 7.2. How Do You Sustain Blockbuster Drugs?; 7.3. The Rise and Decline of the Pharmaceutical Industry; APPENDIX: CHEMICAL STRUCTURES OF THE DRUGS; BIBLIOGRAPHY; INDEX; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z.