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Scaffold hopping in medicinal chemistry /
This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects. The first section serves as an introduction to the topic by describing the concept of scaffolds, their discovery, diversi...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Weinheim, Germany :
Wiley-VCH Verlag GmbH & Co., KGaA,
2013.
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| Colección: | Methods and principles in medicinal chemistry ;
v. 58. |
| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects. The first section serves as an introduction to the topic by describing the concept of scaffolds, their discovery, diversity and representation, and their importance for finding new chemical entities. The following part describes the most common tools and methods for scaffold hopping, whether topological, shape-based or structure-based. Methods such as CATS, Feature Trees, Feature Point Pharmacophores (FEPOPS), and S. |
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| Descripción Física: | 1 online resource (326 pages) : illustrations (some color) |
| Bibliografía: | Includes bibliographical references and index. |
| ISBN: | 9783527665174 352766517X 9783527665167 3527665161 9783527665150 3527665153 9783527665143 3527665145 9781306091008 1306091004 |