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Wnt signaling in development and disease : molecular mechanisms and biological functions /
"Widely recognized as one of the most important signaling mechanisms in development and disease, Wnt signaling pathways are networks of proteins that play significant roles in embryogenesis or cancer development. Wnt Signaling in Development and Disease addresses the fundamentals of Wnt signali...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, New Jersey :
Wiley Blackwell,
[2014]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 037 | |n Title subscribed to via ProQuest Academic Complete | ||
| 042 | |a pcc | ||
| 050 | 0 | 0 | |a QP552.W58 |
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| 072 | 7 | |a SCI |x 007000 |2 bisacsh | |
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| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Wnt signaling in development and disease : |b molecular mechanisms and biological functions / |c [edited by] Stefan Hoppler, Randall T. Moon. |
| 264 | 1 | |a Hoboken, New Jersey : |b Wiley Blackwell, |c [2014] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a "Widely recognized as one of the most important signaling mechanisms in development and disease, Wnt signaling pathways are networks of proteins that play significant roles in embryogenesis or cancer development. Wnt Signaling in Development and Disease addresses the fundamentals of Wnt signaling and delves into molecular pathway mechanisms, its role in embryogenesis, adult tissue homeostasis, and chronic disease. This comprehensive resource details current knowledge of Wnt signaling while looking ahead to future progress"--Provided by publisher | ||
| 588 | 0 | |a Print version record and CIP data provided by publisher. | |
| 505 | 0 | |a Wnt Signaling in Development and Disease; Copyright; Contents; Contributors; Preface; Part 1 Molecular Signaling Mechanisms: From Pathways to Networks; 1 Wnt Signal Production, Secretion, and Diffusion; Introduction; Posttranslational modification of Wnt; The Wnt secretion pathway; Mechanisms that promote and control the diffusion of Wnt; Conclusions and perspectives; References; 2 Wnt Signaling at the Membrane; Introduction; The Frizzled family of Wnt receptors; The LRP family of Wnt coreceptors; References | |
| 505 | 8 | |a Wnt/rho/ ROCK and Wnt/rac/ JNK signalingWnt/Ror signaling; Wnt/Ryk signaling; Wnt/ cAMP /protein kinase A; Wnt/ TOR signaling; Outlook; References; 7 Molecular Mechanisms of Wnt Pathway Specificity; Early Wnt classifications; Wnt5a exemplifies the ability of Wnts to activate multiple signaling cascades; Multiple signaling routes through single Frizzled family members; Determinants of Wnt pathway specificity; Perspectives; Acknowledgments; References; 8 Modulation of Wnt Signaling by Endocytosis of Receptor Complexes; Introduction; Endocytic pathways | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Wnt proteins. | |
| 650 | 0 | |a Cellular signal transduction. | |
| 650 | 1 | 2 | |a Wnt Proteins |x physiology |
| 650 | 2 | |a Wnt Proteins | |
| 650 | 2 | |a Signal Transduction | |
| 650 | 6 | |a Protéines Wnt. | |
| 650 | 6 | |a Transduction du signal cellulaire. | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biochemistry. |2 bisacsh | |
| 650 | 7 | |a Cellular signal transduction |2 fast | |
| 650 | 7 | |a Wnt proteins |2 fast | |
| 700 | 1 | |a Hoppler, Stefan, |d 1965- |e editor. | |
| 700 | 1 | |a Moon, Randall T., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Wnt signaling in development and disease. |d Hoboken, New Jersey : John Wiley & Sons, [2014] |z 9781118444160 |w (DLC) 2013042745 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=1638229 |z Texto completo |
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