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The Wiley-Blackwell Handbook of Psychoneuroimmunology.

This comprehensive resource details the history, methodology and development of research into psychoneuroimmunology, balancing it with meticulous coverage of both the clinical aspects and practical applications of the subject. A much-needed reference including overviews of key advances in the fieldD...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Kusnecov, Alexander W.
Otros Autores: Anisman, Hymie
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken : Wiley, 2013.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • The Wiley-Blackwell Handbook of Psychoneuroimmunology; Contents; Preface; Foreword; List of Contributors; 1 Basic Principles in Immunology: Relevance for Studies in Psychoneuroimmunology; Introduction; The Components of the Immune System; Cytokines and chemokines
  • the immune system's messengers; The cells of the immune system; Modes of Immunity; The Immune System and the Brain; Methods in Immunology with Relevance for Psychoneuroimmunology; Lipopolysaccharides; Nucleic acids; Superantigens; Proteins; Cytokines; Live infectious agents.
  • Immune Processes and their Clinical Consequences on Mental HealthConcluding Remarks; References; 2 Innervation of the Immune System; Basic Organization of the Autonomic and Sensory Systems; Overview of the ANS; Overview of the sensory system; Innervation of Lymphoid Organs; Bone marrow; Thymus; Spleen; Lymph nodes; Functional significance of sympathetic innervation in secondary lymphoid organs: lymph nodes and spleen; Innervation of Diffuse Lymphatic Tissue or Mucosa-Associated Lymphoid Tissue (MALT); No Parasympathetic Innervation of Immune Organs.
  • The Role of the Vagus Nerve and the Cholinergic Anti-inflammatory ReflexSensory Innervation of Immune Organs; The Role of Sensory Nerves in Immune Regulation; Summary of Innervation of the Immune System; References; 3 In Vitro and In Vivo Assessment of Immune System Modulation of Brain Function and Neurochemistry; Overview; Approaches to Assessing Brain Changes Associated with Immune and Cytokine Challenges; Analysis of brain neurochemistry; Analysis of Neuron Function Alterations by Cytokines; Neuronal cell culture; Brain slices; In vivo recordings.
  • What has electrophysiology told us about immune function and brain activity?Summary; Acknowledgments; References; 4 Control and Contributions of the Blood-Brain Barriers to Cytokine Levels in the CNS; Overview; The Blood-Brain Barrier; The Blood-Brain Barrier and the Immune Privileged CNS; Restrictive barrier function; The transport of cytokines across the BBB; Secretion of immunoactive substances by the BBBs; Other mechanisms by which the BBB could control brain cytokines; Conclusions; References; 5 The Immune-Neuroendocrine Network in Health and Disease; Introduction.
  • Historical Perspective and Views: The Immune and Nervous System Talk to Each OtherCytokines Mediate a Resetting of the INE Network During Immune and Inflammatory Responses; Cytokines can take command of homeostasis during disease; The neuronal-cytokine network in the healthy brain; Pathophysiological Consequences of Alterations in the INE Network; Disruption of immune-brain communication during autoimmune, lymphoproliferative, and inflammatory diseases; Deleterious Effects of the INE Network During Prolonged Infections: Pulmonary Tuberculosis as an Example; Conclusions and Proposal.