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Working in biosafety level 3 and 4 laboratories : a practical introduction /
The first training manual for new staff working in BSL3/4 labs. This guide is based on a course developed in 2007 by the EU COST action group 28b which serves as a standard for many courses BSL3/4 training courses worldwide. The four-day course consists of lectures and practical training with the le...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Weinheim :
Wiley Blackwell,
[2014]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Working in Biosafety Level 3 and 4 Laboratories; Contents; Acknowledgement; Preface; List of Contributors; Introduction; References; 1 Laboratory Biosafety in Containment Laboratories; 1.1 Routes of Infection; 1.2 Classification of Microorganisms; 1.3 General Containment Principles; 1.4 Specific Containment Principles; 1.4.1 Biosafety Level 1 Laboratory; 1.4.2 Biosafety Level 2 Laboratory; 1.4.3 Biosafety Level 3 Laboratory; 1.4.4 Biosafety Level 4 Laboratory; 1.5 Design of a Suit-Based-BSL-4 Laboratory with Negative Pressure; 1.6 Safety Routines; Summary; References
- 2 Hazard Criteria and Categorization of Microbes Classification Systems2.1 Facility Requirements; 2.2 Exceptions to the Rules; Summary; 3 Technical and Practical Aspects of BSL-3 Laboratories; 3.1 Technical Aspects-Facilities, Secondary Barriers; 3.1.1 Air Filtration Systems; 3.1.2 Water; 3.1.3 Fire Protection; 3.2 Practical Aspects-Safety Equipment, Primary Barriers; 3.2.1 Staff; 3.3 Personal Protective Equipment (PPE); 3.3.1 Primary Barriers and Working Procedures; Summary; References; 4 Animal Biosafety Level 3 Facility
- Enhancements When Dealing with Large Animals
- 4.1 Enhancements to Upgrade a Standard Animal ABSL-3 Facility to a LABSL-3 Facility Housing Large Animals4.2 Additional Recommendations; Summary; References; 5 Personal Protective Equipment; 5.1 Definitions; 5.2 Regulatory Background; 5.3 Routes of Entry and Types of PPE; 5.4 Use of PPE; Summary; 6 Shipping of Infectious Substances According IATA-DGR Regulations; 6.1 Introduction; 6.2 Classifications and UN Code; 6.3 Limitations; 6.4 Packaging; 6.5 Packing Instruction 650 for Biological Substance, Category B; 6.6 Packing Instruction 620 for Infectious Substance, Category A
- UN 2814 and UN 29006.7 Packing Instruction 904 (UN 1845) for Dry Ice; 6.8 Documentation; Summary; References; 7 Disinfection and Decontamination; 7.1 Introduction; 7.2 Ways of Decontamination/Disinfection; 7.3 Physical Disinfection/Decontamination; 7.4 Irradiation; 7.5 Factors Influencing Chemical Disinfection/Decontamination; 7.5.1 Temperature; 7.5.2 Time of Contact; 7.5.3 Microorganism; 7.5.4 Surface Type (Absorbant vs Nonabsorbant); 7.5.5 Liquid; 7.5.6 pH; 7.5.7 Presence and Type of Dirt; 7.5.8 Concentration of the Product; 7.5.9 High-Pressure Water Cleaning; 7.5.10 Water Used
- 7.5.11 Mechanism/Methods of Decontamination7.5.12 Inoculum Concentration; 7.6 Testing the Activity of a Certain Product; 7.6.1 Physical Disinfection; 7.6.2 Chemical Disinfection; 7.6.2.1 Introduction; 7.6.2.2 Phase 1 Studies; 7.6.2.3 Phase 2 Studies; 7.6.2.4 Phase 3 Studies; 7.7 Chemical Compounds Used as Disinfectants; 7.7.1 Introduction; 7.7.2 Phenols; 7.7.3 Chlorine Derivatives; 7.7.4 Iodophores; 7.7.5 Quaternary Ammonium Compounds; 7.7.6 Amphoteres; 7.7.7 Aldehydes; 7.7.8 Calcium Oxide, Lime; 7.7.9 Alcohols; 7.7.10 Chlorhexidine; 7.7.11 Peroxides; 7.7.12 Peracetic Acid