V-Myb proteins and their oncogenic potential : a study on how two point mutations affect the interaction of v-Myb with other proteins /

The oncogene v-myb of the retroviruses AMV (avian myeloblastosis virus) and E26 (avian leukaemia virus) encodes a transcription factor (v-Myb) which is a truncated homolog of its cellular progenitor c-Myb. c-Myb plays an essential role in the development of haematopoietic cells and is known to be a...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Wienert, Beeke
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hamburg : Diplomica Verlag, 2012.
Temas:
Protein-protein interactions.
Oncogenic viruses.
Proteins.
Oncogenic Viruses
Interactions protéine-protéine.
Virus oncogènes.
Protéines.
protein.
SCIENCE > Life Sciences > Biology.
SCIENCE > Life Sciences > Microbiology.
Oncogenic viruses
Protein-protein interactions
Proteins
Acceso en línea:Texto completo
Descripción
Sumario:The oncogene v-myb of the retroviruses AMV (avian myeloblastosis virus) and E26 (avian leukaemia virus) encodes a transcription factor (v-Myb) which is a truncated homolog of its cellular progenitor c-Myb. c-Myb plays an essential role in the development of haematopoietic cells and is known to be a regulator for many target genes. v-Myb AMV is responsible for the transformation of myelomonocytic cells and for arresting them in an immature stage, presumably because of a deregulation of the expression of specific target genes. In addition to the truncation of the coding region, a number of amino.
Notas:Cover title.
Descripción Física:1 online resource (vii, 107 pages) : illustrations
Bibliografía:Includes bibliographical references.
ISBN:9783842832916
3842832915
3842882912
9783842882911

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