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Paternal influences on human reproductive success /
[Publisher-supplied data] Historically, sperm have been seen as simply a mechanism of transferring a haploid set of chromosomes to the oocyte. However, data from assisted reproduction therapies (ART) have demonstrated that in many couples the sperm appears to be responsible for abnormal embryogenesi...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge :
Cambridge University Press,
2013.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- [Publisher-supplied data] Part I. Advances in Understanding the Male Gamete: 1. The reproductive fitness of the human male gamete Douglas T. Carrell; 2. The sperm genome: effect of aneuploidies, structural variations, single nucleotide changes and DNA damage on embryogenesis and development Kenneth I. Aston and Donald F. Conrad; 3. The sperm epigenome: a role in embryogenesis and fetal health? Douglas T. Carrell and Jessie Dorais; 4. Imprinted gene anomalies in sperm C. Joana Marques and Mário Sousa; 5. Has the renewed interest in sperm RNA led to fresh insights? A critical review and hypothesis David Miller and David Iles; 6. The role of the sperm centrosome in reproductive fitness Heide Schatten and Qing-Yuan Sun; Part II. The Influence of Aging and Environmental Factors on Male Reproductive Fitness: 7. The male biological clock Harry Fisch; 8. The role of aging on fecundity in the male Csilla Krausz and Chiara Chianese; 9. Aging, DNA damage, and reproductive outcome Aleksander Giwercman and Jens Peter Bonde; 10. Paternal aging and increased risk of congenital disease, psychiatric disorders, and cancer Simon L. Conti and Michael L. Eisenberg; 11. Sexual function in the aging male John R. Gannon, Jeremy B. Myers and William O. Brant; 12. Supplements and replacement therapies for the aging male and their effects on reproductive fitness Armand Zini and Naif Al-hathal; 13. Environment and lifestyle effects on fertility Marc A. Beal and Christopher M. Somers; 14. Obesity and male infertility: is there an effect on embryogenesis? Oumar Kuzbari and Ahmad O. Hammoud; Part III. Clinical Laboratory Concepts and Considerations: 15. ICSI: does the sperm matter? Gianpiero D. Palermo, Queenie V. Neri and Zev Rosenwaks; 16. Sperm selection and ART outcome: a means to overcome the effects of aging and abnormal spermatogenesis? Denny Sakkas; 17. Variability of human semen quality: caution in interpreting semen analysis data Kenneth I. Aston; 18. Semen characteristics and aging: technical considerations regarding variability Lars Björndahl.